Detailed information NTG1117058

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EJ102_RS24775
• Genome accession: NZ_LR130530
• Coordinates: 5230732..5232069 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa isolate paerg003
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5225732..5237069

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJ102_RS24750 (BANRA_04805)	pgeF	5225875..5226603 (-)	729	WP_014603307.1	peptidoglycan editing factor PgeF	-
EJ102_RS24755 (BANRA_04806)	rluD	5226600..5227562 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EJ102_RS24760 (BANRA_04807)	-	5227708..5228733 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
EJ102_RS24765 (BANRA_04808)	-	5228890..5229135 (+)	246	WP_014603308.1	PP0621 family protein	-
EJ102_RS24770 (BANRA_04809)	pilS	5229125..5230717 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
EJ102_RS24775 (BANRA_04810)	pilR	5230732..5232069 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
EJ102_RS24780 (BANRA_04811)	thiO	5232115..5233209 (-)	1095	WP_020750388.1	glycine oxidase ThiO	-
EJ102_RS24785 (BANRA_04812)	-	5233344..5233853 (+)	510	WP_003161431.1	GspH/FimT family pseudopilin	-
EJ102_RS24790 (BANRA_04813)	-	5233959..5234465 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
EJ102_RS24795 (BANRA_04814)	pilV	5234456..5235013 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
EJ102_RS24800 (BANRA_04815)	pilW	5235010..5235834 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
EJ102_RS24805 (BANRA_04816)	pilX	5235831..5236418 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1117058 EJ102_RS24775 WP_003094694.1 5230732..5232069(+) (pilR) [Pseudomonas aeruginosa isolate paerg003]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1117058 EJ102_RS24775 WP_003094694.1 5230732..5232069(+) (pilR) [Pseudomonas aeruginosa isolate paerg003]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384