Detailed information NTG1117014

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EJN10_RS08155
• Genome accession: NZ_LR130528
• Coordinates: 1712492..1713829 (-)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa isolate paerg000
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 1707492..1718829

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJN10_RS08125 (BANRA_01578)	pilX	1708143..1708730 (-)	588	WP_023114842.1	type 4a pilus minor pilin PilX	-
EJN10_RS08130 (BANRA_01579)	pilW	1708727..1709551 (-)	825	WP_023114841.1	type 4a pilus minor pilin PilW	-
EJN10_RS08135 (BANRA_01580)	pilV	1709548..1710105 (-)	558	WP_003094697.1	type 4a pilus minor pilin PilV	Machinery gene
EJN10_RS08140 (BANRA_01581)	-	1710096..1710602 (-)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
EJN10_RS08145 (BANRA_01582)	-	1710708..1711217 (-)	510	WP_017002065.1	GspH/FimT family pseudopilin	-
EJN10_RS08150 (BANRA_01583)	thiO	1711352..1712446 (+)	1095	WP_023114840.1	glycine oxidase ThiO	-
EJN10_RS08155 (BANRA_01584)	pilR	1712492..1713829 (-)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
EJN10_RS08160 (BANRA_01585)	pilS	1713844..1715436 (-)	1593	WP_003110428.1	two-component system sensor histidine kinase PilS	Regulator
EJN10_RS08165 (BANRA_01586)	-	1715426..1715671 (-)	246	WP_003102591.1	PP0621 family protein	-
EJN10_RS08170 (BANRA_01587)	-	1715828..1716853 (-)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
EJN10_RS08175 (BANRA_01588)	rluD	1716999..1717961 (+)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EJN10_RS08180 (BANRA_01589)	pgeF	1717958..1718686 (+)	729	WP_004352764.1	peptidoglycan editing factor PgeF	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1117014 EJN10_RS08155 WP_003094694.1 1712492..1713829(-) (pilR) [Pseudomonas aeruginosa isolate paerg000]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1117014 EJN10_RS08155 WP_003094694.1 1712492..1713829(-) (pilR) [Pseudomonas aeruginosa isolate paerg000]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGTGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384