Detailed information NTG1116979

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EJN50_RS09220
• Genome accession: NZ_LR130527
• Coordinates: 1911334..1912671 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa isolate paerg002
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 1906334..1917671

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJN50_RS09195 (BANRA_01794)	pgeF	1906477..1907205 (-)	729	WP_014603307.1	peptidoglycan editing factor PgeF	-
EJN50_RS09200 (BANRA_01795)	rluD	1907202..1908164 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EJN50_RS09205 (BANRA_01796)	-	1908310..1909335 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
EJN50_RS09210 (BANRA_01797)	-	1909492..1909737 (+)	246	WP_014603308.1	PP0621 family protein	-
EJN50_RS09215 (BANRA_01798)	pilS	1909727..1911319 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
EJN50_RS09220 (BANRA_01799)	pilR	1911334..1912671 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
EJN50_RS09225 (BANRA_01800)	thiO	1912717..1913811 (-)	1095	WP_020750388.1	glycine oxidase ThiO	-
EJN50_RS09230 (BANRA_01801)	-	1913946..1914455 (+)	510	WP_003161431.1	GspH/FimT family pseudopilin	-
EJN50_RS09235 (BANRA_01802)	-	1914561..1915067 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
EJN50_RS09240 (BANRA_01803)	pilV	1915058..1915615 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
EJN50_RS09245 (BANRA_01804)	pilW	1915612..1916436 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
EJN50_RS09250 (BANRA_01805)	pilX	1916433..1917020 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1116979 EJN50_RS09220 WP_003094694.1 1911334..1912671(+) (pilR) [Pseudomonas aeruginosa isolate paerg002]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1116979 EJN50_RS09220 WP_003094694.1 1911334..1912671(+) (pilR) [Pseudomonas aeruginosa isolate paerg002]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384