Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   EW024_RS02375 Genome accession   NZ_LR130237
Coordinates   427536..428537 (+) Length   333 a.a.
NCBI ID   WP_002985680.1    Uniprot ID   A0A4U7H1B9
Organism   Streptococcus pyogenes strain SP444 isolate SP444     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 422536..433537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW024_RS02350 - 423210..423893 (-) 684 WP_011017476.1 DUF969 domain-containing protein -
  EW024_RS02355 - 424104..425030 (-) 927 WP_002990711.1 glycosyltransferase family 2 protein -
  EW024_RS02360 - 425175..425552 (-) 378 WP_002985686.1 VOC family protein -
  EW024_RS02365 - 425563..426228 (-) 666 WP_121158073.1 NAD(P)H-dependent oxidoreductase -
  EW024_RS02370 - 426277..427362 (-) 1086 WP_011528361.1 aminopeptidase P family protein -
  EW024_RS02375 ccpA 427536..428537 (+) 1002 WP_002985680.1 catabolite control protein A Regulator
  EW024_RS02380 - 428668..429666 (+) 999 WP_002985678.1 glycosyltransferase family 4 protein -
  EW024_RS02385 - 429668..431002 (+) 1335 WP_011528362.1 glycosyltransferase family 4 protein -
  EW024_RS02390 thrS 431424..433367 (+) 1944 WP_011528363.1 threonine--tRNA ligase -

Sequence

Protein


Download         Length: 333 a.a.        Molecular weight: 36713.83 Da        Isoelectric Point: 5.9985

>NTDB_id=1116559 EW024_RS02375 WP_002985680.1 427536..428537(+) (ccpA) [Streptococcus pyogenes strain SP444 isolate SP444]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide


Download         Length: 1002 bp        

>NTDB_id=1116559 EW024_RS02375 WP_002985680.1 427536..428537(+) (ccpA) [Streptococcus pyogenes strain SP444 isolate SP444]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(177-332)

Bacterial regulatory proteins, lacI family (LacI)

(8-53)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U7H1B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Streptococcus gordonii str. Challis substr. CH1

78.078

100

0.781
  ccpA Streptococcus pneumoniae D39

75.375

100

0.754
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

56.193

99.399

0.559

Multiple sequence alignment