Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   EQB46_RS10060 Genome accession   NZ_LR129843
Coordinates   1830828..1831781 (-) Length   317 a.a.
NCBI ID   WP_000345099.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 180-2 isolate 180-2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1825828..1836781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB46_RS10035 - 1826589..1827212 (-) 624 WP_000932635.1 hypothetical protein -
  EQB46_RS10040 jag 1827263..1828249 (-) 987 WP_000260014.1 RNA-binding cell elongation regulator Jag/EloR -
  EQB46_RS10045 - 1828268..1829092 (-) 825 WP_001809383.1 membrane protein insertase YidC -
  EQB46_RS10050 rnpA 1829067..1829438 (-) 372 WP_000739244.1 ribonuclease P protein component -
  EQB46_RS12025 - 1829455..1829586 (-) 132 WP_000768904.1 hypothetical protein -
  EQB46_RS10055 - 1829587..1830777 (-) 1191 WP_000167765.1 acetate kinase -
  EQB46_RS10060 comYH 1830828..1831781 (-) 954 WP_000345099.1 class I SAM-dependent methyltransferase Machinery gene
  EQB46_RS10065 - 1831842..1832436 (-) 595 Protein_1879 class I SAM-dependent methyltransferase -
  EQB46_RS10070 comGG/cglG 1832573..1832986 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQB46_RS10075 comGF/cglF 1832964..1833425 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQB46_RS10080 comGE/cglE 1833388..1833690 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQB46_RS10085 comGD/cglD 1833653..1834057 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQB46_RS10090 comGC/cglC 1834050..1834376 (-) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  EQB46_RS10095 comGB/cglB 1834378..1835394 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQB46_RS10100 comGA/cglA/cilD 1835342..1836283 (-) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  EQB46_RS10105 - 1836359..1836724 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35718.89 Da        Isoelectric Point: 4.2474

>NTDB_id=1116376 EQB46_RS10060 WP_000345099.1 1830828..1831781(-) (comYH) [Streptococcus pneumoniae strain 180-2 isolate 180-2]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=1116376 EQB46_RS10060 WP_000345099.1 1830828..1831781(-) (comYH) [Streptococcus pneumoniae strain 180-2 isolate 180-2]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAGACTGAGCTAGAACAGGTCAAAGACAACAATC
AGACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTACTTTTGGTGTTTATTGTGGAAGAGCTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTTTGGGCGCTACTTTCTTGACCTCGCTTACTAAAA
AGGTGGATTATTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.952

98.738

0.543
  comYH Streptococcus mutans UA159

54.633

98.738

0.539

Multiple sequence alignment