Detailed information NTG1116297

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQB42_RS09790
• Genome accession: NZ_LR129841
• Coordinates: 1848339..1849349 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 947 isolate 947
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1843339..1854349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQB42_RS09765	-	1844685..1844978 (-)	294	WP_000977363.1	hypothetical protein	-
EQB42_RS09770	-	1845140..1845592 (+)	453	WP_000079148.1	universal stress protein	-
EQB42_RS09775	-	1845627..1847015 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
EQB42_RS09780	-	1847081..1848043 (+)	963	WP_001124777.1	asparaginase	-
EQB42_RS09785	-	1848072..1848275 (-)	204	WP_001813553.1	hypothetical protein	-
EQB42_RS09790	ccpA	1848339..1849349 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQB42_RS09795	-	1849773..1850372 (-)	600	WP_000866698.1	response regulator transcription factor	-
EQB42_RS09800	-	1850373..1851470 (-)	1098	WP_000893537.1	sensor histidine kinase	-
EQB42_RS09805	-	1851470..1852207 (-)	738	WP_050131518.1	ABC transporter permease	-
EQB42_RS09810	-	1852209..1853093 (-)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
EQB42_RS09815	-	1853080..1853274 (-)	195	WP_000820182.1	hypothetical protein	-
EQB42_RS09820	-	1853271..1853477 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=1116297 EQB42_RS09790 WP_000990607.1 1848339..1849349(-) (ccpA) [Streptococcus pneumoniae strain 947 isolate 947]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1116297 EQB42_RS09790 WP_000990607.1 1848339..1849349(-) (ccpA) [Streptococcus pneumoniae strain 947 isolate 947]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568