Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   EQB41_RS10055 Genome accession   NZ_LR129840
Coordinates   1859029..1859649 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain 4496 isolate 4496     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1854029..1864649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB41_RS10030 recA 1854406..1855572 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  EQB41_RS10035 cinA 1855627..1856883 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  EQB41_RS10040 brpA 1856968..1857984 (-) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  EQB41_RS10045 - 1857992..1858510 (-) 519 WP_000455536.1 GNAT family N-acetyltransferase -
  EQB41_RS10050 tsaE 1858500..1858943 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  EQB41_RS10055 comM 1859029..1859649 (-) 621 WP_000839908.1 hypothetical protein Regulator
  EQB41_RS10065 - 1860032..1860895 (-) 864 WP_050199571.1 helix-turn-helix domain-containing protein -
  EQB41_RS10070 - 1861084..1861254 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  EQB41_RS10075 - 1861569..1861865 (+) 297 Protein_1892 lactococcin 972 family bacteriocin -
  EQB41_RS10080 - 1861968..1863983 (+) 2016 WP_000732390.1 DUF1430 domain-containing protein -
  EQB41_RS10085 - 1863985..1864617 (+) 633 WP_000571420.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=1116217 EQB41_RS10055 WP_000839908.1 1859029..1859649(-) (comM) [Streptococcus pneumoniae strain 4496 isolate 4496]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=1116217 EQB41_RS10055 WP_000839908.1 1859029..1859649(-) (comM) [Streptococcus pneumoniae strain 4496 isolate 4496]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCTTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment