Detailed information NTG1116133

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SP119_RS02300
• Genome accession: NZ_LR031521
• Coordinates: 414091..415092 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain S119 isolate S119
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 409091..420092

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP119_RS02275 (SP119_0394)	-	409765..410448 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
SP119_RS02280 (SP119_0395)	-	410659..411585 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
SP119_RS02285 (SP119_0396)	-	411730..412107 (-)	378	WP_002985686.1	VOC family protein	-
SP119_RS02290 (SP119_0397)	-	412118..412783 (-)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
SP119_RS02295 (SP119_0398)	-	412832..413917 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
SP119_RS02300 (SP119_0399)	ccpA	414091..415092 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
SP119_RS02305 (SP119_0400)	-	415223..416221 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
SP119_RS02310 (SP119_0401)	-	416223..417557 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
SP119_RS02315 (SP119_0402)	thrS	417979..419922 (+)	1944	WP_010921984.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1116133 SP119_RS02300 WP_002985680.1 414091..415092(+) (ccpA) [Streptococcus pyogenes strain S119 isolate S119]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1116133 SP119_RS02300 WP_002985680.1 414091..415092(+) (ccpA) [Streptococcus pyogenes strain S119 isolate S119]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559