Detailed information
Bioinformatically predicted
Overview
| Name | comR | Type | Regulator |
| Locus tag | HAS68_RS00360 | Genome accession | NZ_CP002007 |
| Coordinates | 60596..61513 (+) | Length | 305 a.a. |
| NCBI ID | WP_002935296.1 | Uniprot ID | - |
| Organism | Streptococcus suis 05HAS68 | ||
| Function | activate transcription of comX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 13840..59709 | 60596..61513 | flank | 887 |
Gene organization within MGE regions
Location: 13840..61513
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HAS68_RS00075 (HAS68_0014) | ftsH | 13840..15810 (+) | 1971 | WP_004194314.1 | ATP-dependent zinc metalloprotease FtsH | - |
| HAS68_RS00080 (HAS68_0015) | comX/sigX | 16136..16606 (+) | 471 | WP_002936602.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| HAS68_RS00185 (HAS68_0016) | mreC | 23908..24744 (+) | 837 | WP_009908845.1 | rod shape-determining protein MreC | - |
| HAS68_RS00190 (HAS68_0017) | mreD | 24734..25249 (+) | 516 | WP_002935339.1 | rod shape-determining protein MreD | - |
| HAS68_RS00195 (HAS68_0018) | - | 25334..26590 (+) | 1257 | WP_002935338.1 | CHAP domain-containing protein | - |
| HAS68_RS00200 (HAS68_0019) | - | 26693..27658 (+) | 966 | WP_024409289.1 | ribose-phosphate diphosphokinase | - |
| HAS68_RS00205 (HAS68_0020) | - | 27749..28927 (+) | 1179 | WP_002935336.1 | pyridoxal phosphate-dependent aminotransferase | - |
| HAS68_RS00210 (HAS68_0021) | recO | 28914..29696 (+) | 783 | WP_002935335.1 | DNA repair protein RecO | - |
| HAS68_RS00215 (HAS68_0022) | plsX | 29693..30700 (+) | 1008 | WP_002935334.1 | phosphate acyltransferase PlsX | - |
| HAS68_RS00220 (HAS68_0023) | - | 30693..30941 (+) | 249 | WP_002935333.1 | phosphopantetheine-binding protein | - |
| HAS68_RS00225 (HAS68_0024) | purC | 31059..31766 (+) | 708 | WP_002935328.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| HAS68_RS00230 (HAS68_0025) | - | 31779..35498 (+) | 3720 | WP_009908856.1 | phosphoribosylformylglycinamidine synthase | - |
| HAS68_RS00235 (HAS68_0026) | purF | 35501..36955 (+) | 1455 | WP_009908857.1 | amidophosphoribosyltransferase | - |
| HAS68_RS00240 (HAS68_0027) | purM | 37011..38033 (+) | 1023 | WP_009908859.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| HAS68_RS00245 (HAS68_0028) | purN | 38030..38581 (+) | 552 | WP_009908860.1 | phosphoribosylglycinamide formyltransferase | - |
| HAS68_RS00250 (HAS68_0029) | purH | 38591..40138 (+) | 1548 | WP_002935323.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
| HAS68_RS00255 (HAS68_0030) | - | 40203..41033 (+) | 831 | WP_002935322.1 | DNA adenine methylase | - |
| HAS68_RS00260 (HAS68_0031) | - | 41023..41814 (+) | 792 | WP_038425698.1 | site-specific DNA-methyltransferase | - |
| HAS68_RS00265 (HAS68_0032) | - | 41792..42718 (+) | 927 | WP_002935320.1 | type II restriction endonuclease | - |
| HAS68_RS00270 (HAS68_0033) | - | 42718..43623 (+) | 906 | WP_002935319.1 | type II restriction endonuclease | - |
| HAS68_RS00275 (HAS68_0034) | purD | 43744..45006 (+) | 1263 | WP_002935318.1 | phosphoribosylamine--glycine ligase | - |
| HAS68_RS00280 (HAS68_0035) | purE | 45032..45519 (+) | 488 | Protein_36 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
| HAS68_RS00285 (HAS68_0036) | purK | 45506..46591 (+) | 1086 | WP_002935314.1 | 5-(carboxyamino)imidazole ribonucleotide synthase | - |
| HAS68_RS00290 (HAS68_0037) | - | 46578..47501 (+) | 924 | WP_002935313.1 | DUF4268 domain-containing protein | - |
| HAS68_RS00295 (HAS68_0038) | purB | 47536..48828 (+) | 1293 | WP_013730055.1 | adenylosuccinate lyase | - |
| HAS68_RS00300 (HAS68_0039) | - | 49340..50164 (+) | 825 | WP_002935311.1 | ABC transporter ATP-binding protein | - |
| HAS68_RS00305 (HAS68_0040) | - | 50157..50891 (+) | 735 | WP_002935310.1 | ABC transporter permease | - |
| HAS68_RS00310 (HAS68_0041) | - | 51212..52156 (+) | 945 | WP_024409330.1 | IS30 family transposase | - |
| HAS68_RS00315 (HAS68_0042) | - | 52277..53005 (+) | 729 | WP_002935309.1 | hypothetical protein | - |
| HAS68_RS00320 (HAS68_0043) | - | 53015..53593 (+) | 579 | WP_002935308.1 | CPBP family intramembrane glutamic endopeptidase | - |
| HAS68_RS00325 | - | 53608..54036 (+) | 429 | WP_002935307.1 | Msa family membrane protein | - |
| HAS68_RS00330 (HAS68_0045) | - | 54029..54901 (+) | 873 | WP_002935305.1 | ABC transporter ATP-binding protein | - |
| HAS68_RS00335 (HAS68_0046) | - | 54907..55677 (+) | 771 | WP_002935304.1 | membrane protein | - |
| HAS68_RS00340 (HAS68_0047) | - | 55680..57392 (+) | 1713 | WP_002935303.1 | ABC transporter ATP-binding protein | - |
| HAS68_RS11550 | - | 57494..57667 (+) | 174 | WP_002935301.1 | hypothetical protein | - |
| HAS68_RS00345 (HAS68_0048) | ruvB | 57962..58963 (+) | 1002 | WP_002935300.1 | Holliday junction branch migration DNA helicase RuvB | - |
| HAS68_RS00350 (HAS68_0049) | - | 58963..59709 (+) | 747 | WP_002935299.1 | GNAT family N-acetyltransferase | - |
| HAS68_RS00355 (HAS68_0050) | - | 59711..60349 (+) | 639 | WP_002935298.1 | HAD-IA family hydrolase | - |
| HAS68_RS00360 (HAS68_0051) | comR | 60596..61513 (+) | 918 | WP_002935296.1 | helix-turn-helix domain-containing protein | Regulator |
Sequence
Protein
Download Length: 305 a.a. Molecular weight: 36252.32 Da Isoelectric Point: 4.6744
>NTDB_id=111573 HAS68_RS00360 WP_002935296.1 60596..61513(+) (comR) [Streptococcus suis 05HAS68]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYNHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYNHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR
Nucleotide
Download Length: 918 bp
>NTDB_id=111573 HAS68_RS00360 WP_002935296.1 60596..61513(+) (comR) [Streptococcus suis 05HAS68]
ATGAACGATAAGGAGTTTGGACAGCGTGTGCGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAAATAGTTGTAGACACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATAATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAATATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA
ATGAACGATAAGGAGTTTGGACAGCGTGTGCGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAAATAGTTGTAGACACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATAATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAATATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comR | Streptococcus suis D9 |
100 |
100 |
1 |
| comR | Streptococcus suis P1/7 |
62.126 |
98.689 |
0.613 |
| comR | Streptococcus suis 05ZYH33 |
62.126 |
98.689 |
0.613 |
| comR | Streptococcus mutans UA159 |
37 |
98.361 |
0.364 |