Detailed information    

insolico Bioinformatically predicted

Overview

Name   comZ   Type   Machinery gene
Locus tag   TTHNP4_RS02265 Genome accession   NZ_LR027517
Coordinates   405238..406914 (-) Length   558 a.a.
NCBI ID   WP_124104347.1    Uniprot ID   A0A3P4ANR0
Organism   Thermus thermophilus isolate TTHNAR1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 400238..411914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TTHNP4_RS02220 (TTHN1_00445) - 400279..400881 (+) 603 WP_124104342.1 DUF1640 domain-containing protein -
  TTHNP4_RS02230 (TTHN1_00447) trpS 401058..402071 (+) 1014 WP_018461708.1 tryptophan--tRNA ligase -
  TTHNP4_RS02235 (TTHN1_00448) - 402068..402724 (+) 657 WP_124104343.1 chromosome segregation protein ScpA -
  TTHNP4_RS02240 (TTHN1_00449) - 402743..403300 (+) 558 WP_124104344.1 Uma2 family endonuclease -
  TTHNP4_RS02245 (TTHN1_00450) - 403334..403696 (-) 363 WP_060384345.1 DUF86 domain-containing protein -
  TTHNP4_RS02250 (TTHN1_00451) - 403683..403982 (-) 300 WP_008631315.1 nucleotidyltransferase family protein -
  TTHNP4_RS02255 (TTHN1_00452) - 404005..404409 (-) 405 WP_353955077.1 Uma2 family endonuclease -
  TTHNP4_RS02260 (TTHN1_00453) - 404597..405022 (-) 426 WP_124104346.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  TTHNP4_RS02265 (TTHN1_00454) comZ 405238..406914 (-) 1677 WP_124104347.1 pilus assembly PilX N-terminal domain-containing protein Machinery gene
  TTHNP4_RS02270 (TTHN1_00455) pilA/pilA3 406925..407626 (-) 702 WP_124104348.1 PilW family protein Machinery gene
  TTHNP4_RS02275 (TTHN1_00456) pilA/pilA2 407623..408129 (-) 507 WP_252973319.1 prepilin Machinery gene
  TTHNP4_RS14420 (TTHN1_00457) - 408699..408962 (+) 264 WP_252973320.1 hypothetical protein -
  TTHNP4_RS02285 (TTHN1_00458) - 409108..409581 (-) 474 WP_124104350.1 GspH/FimT family protein -
  TTHNP4_RS02290 (TTHN1_00459) pilA/pilA1 409637..410107 (-) 471 WP_124104351.1 GspH/FimT family protein Machinery gene
  TTHNP4_RS02295 (TTHN1_00460) - 410265..411245 (+) 981 WP_124104352.1 YpdA family putative bacillithiol disulfide reductase -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 59730.45 Da        Isoelectric Point: 8.6977

>NTDB_id=1115716 TTHNP4_RS02265 WP_124104347.1 405238..406914(-) (comZ) [Thermus thermophilus isolate TTHNAR1]
MNRKGIALVATLALMVVIALLVFGTFFTTQIELWTTRNDTTSVQAFYAAEAGLQKYKAALFQQYVWREQQGGTGGGGGCF
TSLARGLDLDRDGTITPFVNNRLVLAQNEVVTDANGNPVGRYTATLYKDAQDGQLFTLVSEGTSGGAKARVQATFRISNT
DYLEQAIFAGSGQANKWLNGGATIRGGVYVVGSPNNLDQYVIEANGNFALYNWYDLNTYSGIANRVEPSYQRAQDLCASL
RVQYGKISVGGSTQIGEPNNKVKGVFVGRGAQDITGQNVGVCQNNKGVCTEAMGGFDLSNPPPFPTLDAKLDSDACSAHS
TWRDCLQTKAALRIQRLGNVPSVARPLGITLPPSCLGAMQSGTLTLDTQSVDCTFTRLDGSRGGFRYTYAGNNRSGQGLL
EVFGDVVLEGVNVVLKKPTDYRVQSGSARSATLAVLQLGGNGGNLDINANLLPDATFGSFPGHVLGLVVEKDLYQRGQYV
MAPVYAGGTFRVVKDNVLFGSVIANQFCTTSAGNQTSCNAGQKAEVVYIRIPKENRPVLLPSLRGGKPVFQVLSYERR

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=1115716 TTHNP4_RS02265 WP_124104347.1 405238..406914(-) (comZ) [Thermus thermophilus isolate TTHNAR1]
GTGAACCGCAAAGGTATCGCCCTCGTAGCCACTTTGGCCCTCATGGTGGTCATCGCCCTCTTGGTCTTCGGCACCTTCTT
CACCACCCAGATAGAGCTCTGGACCACCCGCAACGACACCACCTCGGTCCAGGCCTTCTACGCCGCCGAAGCAGGCTTAC
AGAAGTACAAGGCCGCCCTCTTCCAGCAGTACGTCTGGCGGGAGCAGCAGGGCGGGACGGGGGGAGGTGGGGGCTGCTTC
ACCTCCCTGGCAAGGGGGCTGGACCTGGACCGGGATGGAACCATCACGCCCTTCGTCAACAACCGGCTGGTCCTGGCGCA
AAACGAGGTGGTCACCGACGCCAACGGAAACCCCGTGGGGCGGTACACGGCAACCCTTTACAAGGACGCCCAAGACGGCC
AGCTCTTCACCCTGGTCTCCGAGGGCACCTCGGGCGGGGCCAAGGCCCGGGTCCAGGCCACCTTCCGCATCAGCAACACG
GACTACCTGGAGCAGGCCATCTTCGCCGGCTCGGGCCAGGCCAACAAGTGGCTGAACGGCGGGGCCACCATCCGGGGCGG
GGTCTACGTGGTAGGAAGCCCTAACAACCTGGACCAGTACGTCATAGAGGCTAACGGCAACTTCGCCCTCTACAACTGGT
ATGACCTTAACACCTACTCCGGGATCGCCAACCGGGTGGAACCCAGCTACCAGCGGGCCCAGGACCTCTGCGCAAGCCTT
AGGGTGCAGTACGGCAAGATTTCCGTGGGAGGAAGCACCCAAATCGGCGAGCCCAACAACAAGGTGAAGGGGGTCTTCGT
GGGCCGGGGCGCCCAGGACATTACCGGCCAGAACGTGGGGGTCTGCCAGAACAACAAGGGGGTCTGCACCGAGGCCATGG
GGGGCTTTGACCTCTCCAACCCGCCGCCCTTCCCGACCCTGGACGCCAAGCTGGACTCCGACGCCTGCAGCGCCCACTCC
ACCTGGCGGGACTGCCTCCAGACCAAGGCCGCTCTACGGATTCAGCGCCTGGGGAACGTGCCCTCCGTGGCTAGACCGCT
TGGAATCACCTTGCCCCCTTCCTGCCTCGGGGCCATGCAGTCCGGCACCCTGACCTTGGATACCCAAAGCGTGGACTGCA
CCTTTACCCGCTTGGACGGAAGCCGGGGGGGGTTCAGGTACACCTATGCGGGGAACAACAGGAGCGGACAGGGGCTTCTG
GAAGTATTCGGCGACGTGGTGCTGGAGGGGGTGAACGTGGTTCTGAAGAAACCCACGGACTACAGGGTCCAATCGGGGAG
TGCCAGGAGCGCCACCCTGGCGGTGCTGCAGCTTGGCGGCAACGGCGGCAACCTGGATATCAACGCCAACCTCCTCCCCG
ATGCCACCTTTGGCTCTTTCCCCGGTCATGTCTTGGGCCTTGTGGTGGAGAAGGACCTCTACCAGCGCGGCCAGTACGTG
ATGGCTCCGGTGTACGCCGGGGGCACCTTCCGGGTGGTGAAGGACAACGTCCTTTTCGGTTCCGTCATCGCCAACCAGTT
CTGCACCACCAGTGCCGGCAACCAAACGAGCTGCAACGCCGGCCAAAAGGCCGAGGTGGTCTACATCCGCATCCCCAAGG
AGAACCGCCCCGTGCTCCTGCCGAGCCTCCGGGGGGGAAAGCCGGTCTTCCAGGTGCTCTCCTATGAGCGCCGCTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3P4ANR0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comZ Thermus thermophilus HB27

89.068

100

0.891

Multiple sequence alignment