Detailed information NTG1115318

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: MIDG2331_RS09655
• Genome accession: NZ_LN908249
• Coordinates: 2053122..2053778 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae serovar 8 isolate MIDG2331
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2048122..2058778

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MIDG2331_RS09635 (MIDG2331_01963)	nanA	2048495..2049373 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
MIDG2331_RS09640 (MIDG2331_01964)	nagB	2049423..2050226 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
MIDG2331_RS09645 (MIDG2331_01965)	nagA	2050278..2051423 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
MIDG2331_RS09650 (MIDG2331_01966)	fumC	2051573..2052967 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
MIDG2331_RS09655 (MIDG2331_01967)	sxy/tfoX	2053122..2053778 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
MIDG2331_RS09660 (MIDG2331_01968)	rpsJ	2054186..2054497 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
MIDG2331_RS09665 (MIDG2331_01969)	rplC	2054523..2055149 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
MIDG2331_RS09670 (MIDG2331_01970)	rplD	2055165..2055767 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
MIDG2331_RS09675 (MIDG2331_01971)	rplW	2055764..2056069 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
MIDG2331_RS09680 (MIDG2331_01972)	rplB	2056090..2056911 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
MIDG2331_RS09685 (MIDG2331_01973)	rpsS	2056939..2057214 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
MIDG2331_RS09690 (MIDG2331_01974)	rplV	2057225..2057557 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
MIDG2331_RS09695 (MIDG2331_01975)	rpsC	2057576..2058283 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
MIDG2331_RS09700 (MIDG2331_01976)	rplP	2058297..2058707 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=1115318 MIDG2331_RS09655 WP_005609196.1 2053122..2053778(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 8 isolate MIDG2331]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=1115318 MIDG2331_RS09655 WP_005609196.1 2053122..2053778(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 8 isolate MIDG2331]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376