Detailed information NTG1114375

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: AT689_RS04020
• Genome accession: NZ_LN831051
• Coordinates: 752414..753424 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain NCTC7465
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 747414..758424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AT689_RS03990 (ERS445053_00775)	-	748284..748490 (+)	207	WP_000503437.1	hypothetical protein	-
AT689_RS03995 (ERS445053_00776)	-	748487..748681 (+)	195	WP_000820179.1	hypothetical protein	-
AT689_RS04000 (ERS445053_00777)	-	748668..749552 (+)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
AT689_RS04005 (ERS445053_00778)	-	749554..750291 (+)	738	WP_000832837.1	ABC transporter permease	-
AT689_RS04010 (ERS445053_00779)	-	750291..751388 (+)	1098	WP_000893532.1	sensor histidine kinase	-
AT689_RS04015 (ERS445053_00780)	-	751390..751989 (+)	600	WP_000866729.1	response regulator transcription factor	-
AT689_RS04020 (ERS445053_00781)	ccpA	752414..753424 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
AT689_RS04025 (ERS445053_00782)	-	753488..753859 (+)	372	WP_001092050.1	hypothetical protein	-
AT689_RS04030 (ERS445053_00783)	-	753856..754818 (-)	963	WP_001124781.1	asparaginase	-
AT689_RS04035 (ERS445053_00784)	-	754884..756272 (+)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
AT689_RS04040 (ERS445053_00785)	-	756307..756759 (-)	453	WP_000079154.1	universal stress protein	-
AT689_RS04045 (ERS445053_00786)	-	756921..757214 (+)	294	WP_000977367.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=1114375 AT689_RS04020 WP_000990607.1 752414..753424(+) (ccpA) [Streptococcus pneumoniae strain NCTC7465]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1114375 AT689_RS04020 WP_000990607.1 752414..753424(+) (ccpA) [Streptococcus pneumoniae strain NCTC7465]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGCTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568