Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   AT683_RS03875 Genome accession   NZ_LN831035
Coordinates   762286..762978 (+) Length   230 a.a.
NCBI ID   WP_038440789.1    Uniprot ID   A0AAJ8WR53
Organism   Haemophilus influenzae strain NCTC8143     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 757286..767978
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT683_RS03855 (ERS450003_00774) ampD 758558..759118 (-) 561 WP_011271974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  AT683_RS03860 (ERS450003_00775) pilA 759233..759682 (+) 450 WP_011271973.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  AT683_RS03865 (ERS450003_00776) pilB 759679..761076 (+) 1398 WP_038440787.1 GspE/PulE family protein Machinery gene
  AT683_RS03870 (ERS450003_00777) pilC 761069..762289 (+) 1221 WP_011271971.1 type II secretion system F family protein Machinery gene
  AT683_RS03875 (ERS450003_00778) pilD 762286..762978 (+) 693 WP_038440789.1 A24 family peptidase Machinery gene
  AT683_RS03880 (ERS450003_00779) rho 763032..764294 (-) 1263 WP_005629550.1 transcription termination factor Rho -
  AT683_RS03885 (ERS450003_00780) metJ 764542..764859 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  AT683_RS03890 (ERS450003_00781) cueR 764873..765259 (-) 387 WP_005663006.1 Cu(I)-responsive transcriptional regulator -
  AT683_RS03895 (ERS450003_00782) - 765336..765542 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  AT683_RS03900 (ERS450003_00783) - 765617..765823 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  AT683_RS03905 (ERS450003_00784) - 765897..766103 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  AT683_RS03910 (ERS450003_00785) - 766177..766383 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  AT683_RS03915 (ERS450003_00786) - 766458..766664 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  AT683_RS03920 (ERS450003_00787) - 766738..766944 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  AT683_RS03925 (ERS450003_00788) - 767018..767224 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  AT683_RS03930 (ERS450003_00789) - 767298..767504 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26786.77 Da        Isoelectric Point: 8.6895

>NTDB_id=1114283 AT683_RS03875 WP_038440789.1 762286..762978(+) (pilD) [Haemophilus influenzae strain NCTC8143]
MIYFTMFLLGGILGIALWFYLSGFITHLQQEIYATYVELFPQNSSPFQPHFASIQQKKCGHILRYFFSIGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGTDNNFSLLTLSESIKSAAIFFIVFYAIYWIAKCYYR
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHRKKKEFLPFAPFMNLSAVIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1114283 AT683_RS03875 WP_038440789.1 762286..762978(+) (pilD) [Haemophilus influenzae strain NCTC8143]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACGCA
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACAGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTTAGTATTGGGGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGCACAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCGGCTATTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAGAAAGAAAAAAGAATTTTTACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

97.391

100

0.974
  pilD Haemophilus influenzae Rd KW20

95.652

100

0.957

Multiple sequence alignment