Detailed information NTG1114138

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: AT700_RS23630
• Genome accession: NZ_LN831024
• Coordinates: 5132969..5134306 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain NCTC10332
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5127969..5139306

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AT700_RS23605 (ERS445055_04833)	pgeF	5128112..5128840 (-)	729	WP_012614543.1	peptidoglycan editing factor PgeF	-
AT700_RS23610 (ERS445055_04834)	rluD	5128837..5129799 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
AT700_RS23615 (ERS445055_04835)	-	5129945..5130970 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
AT700_RS23620 (ERS445055_04836)	-	5131127..5131372 (+)	246	WP_003102591.1	PP0621 family protein	-
AT700_RS23625 (ERS445055_04837)	pilS	5131362..5132954 (+)	1593	WP_003110428.1	two-component system sensor histidine kinase PilS	Regulator
AT700_RS23630 (ERS445055_04838)	pilR	5132969..5134306 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
AT700_RS23635 (ERS445055_04839)	thiO	5134352..5135446 (-)	1095	WP_031801325.1	glycine oxidase ThiO	-
AT700_RS23640 (ERS445055_04840)	-	5135581..5136090 (+)	510	WP_003102595.1	GspH/FimT family pseudopilin	-
AT700_RS23645 (ERS445055_04841)	-	5136196..5136702 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
AT700_RS23650 (ERS445055_04842)	pilV	5136693..5137250 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
AT700_RS23655 (ERS445055_04843)	pilW	5137247..5138071 (+)	825	WP_048521676.1	type 4a pilus minor pilin PilW	-
AT700_RS23660 (ERS445055_04844)	pilX	5138068..5138655 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1114138 AT700_RS23630 WP_003094694.1 5132969..5134306(+) (pilR) [Pseudomonas aeruginosa strain NCTC10332]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1114138 AT700_RS23630 WP_003094694.1 5132969..5134306(+) (pilR) [Pseudomonas aeruginosa strain NCTC10332]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGTGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAAAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384