Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DR76_RS05925 Genome accession   NZ_CP009072
Coordinates   1266758..1267390 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli ATCC 25922     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1261758..1272390
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DR76_RS05900 (DR76_1137) yhfG 1261890..1262057 (+) 168 WP_000736858.1 YhfG family protein -
  DR76_RS05905 (DR76_1138) fic 1262047..1262649 (+) 603 WP_001280638.1 putative adenosine monophosphate-protein transferase Fic -
  DR76_RS05910 (DR76_1139) pabA 1262681..1263244 (+) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  DR76_RS05915 (DR76_1140) argD 1263330..1264550 (+) 1221 WP_000963800.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  DR76_RS05920 (DR76_1141) yhfK 1264617..1266707 (-) 2091 WP_001304921.1 YccS/YhfK family putative transporter -
  DR76_RS05925 (DR76_1142) crp 1266758..1267390 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  DR76_RS05935 (DR76_1143) yhfA 1267692..1268096 (+) 405 WP_001148908.1 OsmC family protein -
  DR76_RS05940 (DR76_1144) prkB 1268151..1269020 (-) 870 WP_001274684.1 phosphoribulokinase -
  DR76_RS05945 (DR76_1145) yheU 1269074..1269292 (-) 219 WP_000907085.1 YheU family protein -
  DR76_RS05950 (DR76_1146) yheT 1269286..1270308 (-) 1023 WP_000057387.1 hydrolase -
  DR76_RS05955 (DR76_1147) yheS 1270308..1272221 (-) 1914 WP_000634808.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=111373 DR76_RS05925 WP_000242755.1 1266758..1267390(-) (crp) [Escherichia coli ATCC 25922]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=111373 DR76_RS05925 WP_000242755.1 1266758..1267390(-) (crp) [Escherichia coli ATCC 25922]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment