Detailed information NTG1113628

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: LFA_RS11490
• Genome accession: NZ_LN614827
• Coordinates: 2788921..2789997 (+)
• Length: 358 a.a.
• NCBI ID: WP_045096316.1
• Uniprot ID: A0A098G8V4
• Organism: Legionella fallonii LLAP-10
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2783921..2794997

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LFA_RS11465 (LFA_2524)	-	2784264..2785016 (-)	753	WP_045096311.1	CPBP family glutamic-type intramembrane protease	-
LFA_RS11470 (LFA_2525)	rsmB	2785013..2786344 (-)	1332	WP_045096312.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
LFA_RS11475 (LFA_2526)	fmt	2786341..2787285 (-)	945	WP_045096313.1	methionyl-tRNA formyltransferase	-
LFA_RS11480 (LFA_2527)	def	2787282..2787797 (-)	516	WP_045096314.1	peptide deformylase	-
LFA_RS11485 (LFA_2528)	-	2787887..2788924 (+)	1038	WP_045096315.1	LysM peptidoglycan-binding domain-containing protein	-
LFA_RS11490 (LFA_2529)	dprA	2788921..2789997 (+)	1077	WP_045096316.1	DNA-processing protein DprA	Machinery gene
LFA_RS11495 (LFA_2530)	-	2789999..2790436 (+)	438	WP_045096317.1	DUF494 family protein	-
LFA_RS11500 (LFA_2531)	topA	2790513..2792801 (+)	2289	WP_045096318.1	type I DNA topoisomerase	-
LFA_RS11505 (LFA_2532)	-	2793367..2794086 (+)	720	WP_045096319.1	haloacid dehalogenase type II	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 39385.60 Da
• Isoelectric Point: 7.0390

>NTDB_id=1113628 LFA_RS11490 WP_045096316.1 2788921..2789997(+) (dprA) [Legionella fallonii LLAP-10]
MNQLPYYLALNRMNKIGPRTIAKLEKRWPNLQEMFQLSAQELESAGLPPLLAHTITTFDLKEIETDLNWMEQSKDHHLLT
WSCANYPQLLKEIADPPVVLYAKGQLSCLQRPTLAIVGSRNPSITGSDNAKQFAKELSTHPLTIVSGLALGIDAQAHIGC
LEVGGQTIAVLGTGIDCIYPQRHRQLAEQITQNGLLLSEFPLKSPPIAGHFPRRNRIISGLSLCILVIEAAIKSGSLITA
RMALEQNRDVLAIPGSIHNPLARGCHYLLQQGAKLVTSVNDVLDELKIEHHTMFTDEKPIFSLASGNKNLVKFIGFETTT
VDQIIKRSGYSVEEVTGQLAELELLGTIVSVPGGYMRC

Nucleotide

• Length: 1077 bp

>NTDB_id=1113628 LFA_RS11490 WP_045096316.1 2788921..2789997(+) (dprA) [Legionella fallonii LLAP-10]
ATGAATCAATTACCCTACTACCTCGCCTTAAATAGAATGAATAAAATTGGCCCAAGAACCATAGCCAAATTAGAAAAACG
TTGGCCTAATTTGCAGGAGATGTTTCAACTCTCCGCCCAAGAATTAGAAAGTGCGGGTTTGCCCCCTTTATTAGCTCATA
CCATTACAACATTTGATCTAAAGGAAATTGAGACGGATTTAAATTGGATGGAACAGAGCAAAGACCATCACTTGTTAACA
TGGAGTTGCGCTAATTATCCCCAGCTATTAAAAGAAATTGCCGATCCACCTGTAGTCTTGTATGCCAAAGGACAACTGTC
TTGCCTTCAACGCCCCACCCTGGCAATTGTTGGCAGCCGTAATCCATCCATCACAGGCAGTGATAATGCCAAACAGTTTG
CCAAAGAACTGTCAACTCACCCACTCACGATTGTCAGTGGTTTAGCTTTAGGAATAGACGCTCAGGCTCATATAGGATGT
TTGGAAGTGGGAGGACAGACGATAGCCGTTTTAGGAACAGGTATTGATTGCATTTATCCTCAACGCCATAGGCAATTAGC
AGAGCAAATTACCCAAAATGGCCTATTACTTTCAGAATTTCCATTAAAAAGTCCGCCAATCGCTGGACATTTTCCACGCA
GAAATCGTATAATAAGTGGTTTGTCATTATGCATTTTGGTTATAGAGGCAGCAATAAAAAGTGGCTCTTTAATCACAGCA
AGAATGGCTTTAGAGCAAAATCGAGATGTATTGGCTATACCAGGCTCCATTCATAATCCATTGGCTCGAGGCTGCCATTA
CTTGTTACAACAAGGTGCTAAATTAGTAACTTCAGTAAATGATGTTCTCGATGAGTTAAAAATTGAACATCATACTATGT
TTACCGACGAGAAACCGATTTTTTCCCTTGCCAGCGGGAATAAAAACCTAGTAAAGTTCATTGGATTTGAAACGACAACA
GTCGATCAAATTATTAAGCGCAGTGGATACAGTGTAGAAGAGGTCACTGGCCAACTTGCAGAATTGGAATTATTAGGAAC
TATTGTATCAGTCCCTGGCGGCTATATGAGGTGTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-277)

• DprA winged helix domain (DprA_WH) (302-354)

3D structure

• AlphaFold DB: A0A098G8V4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Legionella pneumophila strain ERS1305867	76.257	100	0.763
dprA	Vibrio campbellii strain DS40M4	45	100	0.453
dprA	Vibrio cholerae strain A1552	43.956	100	0.447
dprA	Glaesserella parasuis strain SC1401	40.267	100	0.422