Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SEB_RS08055 Genome accession   NZ_HG813242
Coordinates   1688682..1689398 (+) Length   238 a.a.
NCBI ID   WP_001829999.1    Uniprot ID   C0LF82
Organism   Staphylococcus epidermidis PM221     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1683682..1694398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SEB_RS08030 (SEB_01648) - 1685081..1685866 (+) 786 WP_002494640.1 carbon-nitrogen family hydrolase -
  SEB_RS12855 hld 1686247..1686324 (-) 78 WP_002494082.1 delta-hemolysin -
  SEB_RS08035 (SEB_01649) - 1686641..1687204 (+) 564 WP_002468344.1 accessory gene regulator AgrB -
  SEB_RS08040 (SEB_01650) - 1687210..1687350 (+) 141 WP_002468352.1 cyclic lactone autoinducer peptide -
  SEB_RS13335 - 1687375..1688665 (+) 1291 Protein_1594 GHKL domain-containing protein -
  SEB_RS08055 (SEB_01653) agrA 1688682..1689398 (+) 717 WP_001829999.1 LytTR family DNA-binding domain-containing protein Regulator
  SEB_RS08060 (SEB_01654) - 1689466..1690425 (-) 960 WP_038399517.1 carbohydrate kinase -
  SEB_RS08065 (SEB_01655) - 1690432..1691904 (-) 1473 WP_002494642.1 sucrose-6-phosphate hydrolase -
  SEB_RS08070 (SEB_01656) - 1692164..1693117 (-) 954 WP_002494643.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.97 Da        Isoelectric Point: 5.6250

>NTDB_id=1112046 SEB_RS08055 WP_001829999.1 1688682..1689398(+) (agrA) [Staphylococcus epidermidis PM221]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1112046 SEB_RS08055 WP_001829999.1 1688682..1689398(+) (agrA) [Staphylococcus epidermidis PM221]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAGCTGACTTATTTGACATTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAAGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCAAAAGAAAGTAATGTAGATACGATTGAGTTAAAGCGGGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGGCTCATTGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ACTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0LF82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374

Multiple sequence alignment