Detailed information NTG1111861

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SPYH293_RS02215
• Genome accession: NZ_HG316453
• Coordinates: 423766..424767 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain H293
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 418766..429767

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYH293_RS02190 (SPYH293_00456)	-	419440..420123 (-)	684	WP_031488436.1	DUF969 domain-containing protein	-
SPYH293_RS02195 (SPYH293_00457)	-	420334..421260 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
SPYH293_RS02200 (SPYH293_00458)	-	421405..421782 (-)	378	WP_002985686.1	VOC family protein	-
SPYH293_RS02205 (SPYH293_00459)	-	421793..422458 (-)	666	WP_031488435.1	NAD(P)H-dependent oxidoreductase	-
SPYH293_RS02210 (SPYH293_00460)	-	422507..423592 (-)	1086	WP_031488434.1	aminopeptidase P family protein	-
SPYH293_RS02215 (SPYH293_00461)	ccpA	423766..424767 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
SPYH293_RS02220 (SPYH293_00462)	-	424898..425896 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
SPYH293_RS02225 (SPYH293_00463)	-	425898..427232 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
SPYH293_RS02230 (SPYH293_00464)	thrS	427654..429597 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1111861 SPYH293_RS02215 WP_002985680.1 423766..424767(+) (ccpA) [Streptococcus pyogenes strain H293]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1111861 SPYH293_RS02215 WP_002985680.1 423766..424767(+) (ccpA) [Streptococcus pyogenes strain H293]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559