Detailed information NTG1111484

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACN076_RS10190
• Genome accession: NZ_CP184836
• Coordinates: 2046065..2047075 (-)
• Length: 336 a.a.
• NCBI ID: WP_001090627.1
• Uniprot ID: I0SX71
• Organism: Streptococcus sp. K0074
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 2041065..2052075

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACN076_RS10165 (ACN076_10165)	-	2041132..2042346 (-)	1215	WP_261446568.1	pyridoxal phosphate-dependent aminotransferase	-
ACN076_RS10170 (ACN076_10170)	-	2042503..2042796 (-)	294	WP_261064245.1	hypothetical protein	-
ACN076_RS10175 (ACN076_10175)	-	2042958..2043410 (+)	453	WP_000079148.1	universal stress protein	-
ACN076_RS10180 (ACN076_10180)	-	2043445..2044833 (-)	1389	WP_261066323.1	Cof-type HAD-IIB family hydrolase	-
ACN076_RS10185 (ACN076_10185)	-	2044899..2045861 (+)	963	WP_261066322.1	asparaginase	-
ACN076_RS10190 (ACN076_10190)	ccpA	2046065..2047075 (-)	1011	WP_001090627.1	catabolite control protein A	Regulator
ACN076_RS10195 (ACN076_10195)	-	2047313..2047630 (+)	318	WP_000886035.1	DUF960 domain-containing protein	-
ACN076_RS10200 (ACN076_10200)	folB	2047675..2048487 (-)	813	WP_261052313.1	dihydroneopterin aldolase	-
ACN076_RS10205 (ACN076_10205)	folE	2048646..2049200 (-)	555	WP_004247172.1	GTP cyclohydrolase I FolE	-
ACN076_RS10210 (ACN076_10210)	-	2049181..2050503 (-)	1323	WP_265528891.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
ACN076_RS10215 (ACN076_10215)	folP	2050505..2051479 (-)	975	WP_371491864.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37169.19 Da
• Isoelectric Point: 5.3350

>NTDB_id=1111484 ACN076_RS10190 WP_001090627.1 2046065..2047075(-) (ccpA) [Streptococcus sp. K0074]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVTYLAKENERIAFVSGPLVDDINGKVRLVGYKEALKKAGISYSEGLVFESKYTYEDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEEFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1111484 ACN076_RS10190 WP_001090627.1 2046065..2047075(-) (ccpA) [Streptococcus sp. K0074]
ATGAATACAGACGATACAGTAACGATTTATGATGTCGCCCGTGAAGCAGGAGTTTCAATGGCGACGGTTAGCCGTGTAGT
CAATGGCAATAAGAATGTAAAAGAGAACACCCGTAAAAAAGTGCTTGAGGTGATTGATCGTTTAGATTACCGTCCAAATG
CTGTGGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTGGTGATCCCAAATATTACCAATGGCTATTTCTCA
ACGCTTGCTAAAGGGATTGACGATATCGCTGAAATGTACAAGTATAATATTGTCCTTGCTAATAGTGATGAGGATGATGA
CAAGGAAGTTTCAGTTGTCAATACCCTGTTTTCTAAGCAAGTGGATGGTATCATCTTTATGGGGTACCACTTGACTGAAA
AAATTCGTTCAGAGTTTTCTCGTTCTCGGACACCAGTTGTTCTTGCAGGAACTGTGGATGTAGAACATCAGCTTCCAAGT
GTCAATATTGACTACAAACAAGCAACGATTGATGCAGTAACCTACCTTGCTAAAGAAAATGAGCGCATCGCTTTTGTTAG
CGGTCCACTAGTGGATGACATCAATGGTAAGGTTCGTTTGGTTGGCTACAAGGAAGCCTTGAAAAAAGCAGGTATTTCTT
ATAGCGAAGGATTGGTATTTGAATCTAAGTACACTTATGAAGACGGTTATGCCTTGGCAGAACGCTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTAACAGGTGATGAATTGGCAGCAGGTGTCTTGAACGGCCTTGCTGATAAGGGTGTGTCTGTGCC
AGAAGAGTTTGAAATCATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACTATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTCGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: I0SX71

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	95.536	100	0.955
ccpA	Streptococcus gordonii str. Challis substr. CH1	89.521	99.405	0.89
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	58.006	98.512	0.571