Detailed information NTG1111142

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACODUA_RS16035
• Genome accession: NZ_CP184748
• Coordinates: 3813546..3814883 (+)
• Length: 445 a.a.
• NCBI ID: WP_014149715.1
• Uniprot ID: G4T4E7
• Organism: Methylotuvimicrobium alcaliphilum 20Z
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 3808546..3819883

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACODUA_RS16020 (ACODUA_16020)	sucD	3809266..3810135 (-)	870	WP_014149712.1	succinate--CoA ligase subunit alpha	-
ACODUA_RS16025 (ACODUA_16025)	sucC	3810132..3811298 (-)	1167	WP_014149713.1	ADP-forming succinate--CoA ligase subunit beta	-
ACODUA_RS16030 (ACODUA_16030)	-	3811918..3813549 (+)	1632	WP_014149714.1	sensor histidine kinase	-
ACODUA_RS16035 (ACODUA_16035)	pilR	3813546..3814883 (+)	1338	WP_014149715.1	sigma-54-dependent transcriptional regulator	Regulator
ACODUA_RS16040 (ACODUA_16040)	-	3815134..3815583 (-)	450	WP_014149716.1	hypothetical protein	-
ACODUA_RS16045 (ACODUA_16045)	-	3815911..3817131 (-)	1221	WP_014149717.1	UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase	-
ACODUA_RS16050 (ACODUA_16050)	ubiH	3817137..3818348 (-)	1212	WP_014149718.1	2-octaprenyl-6-methoxyphenyl hydroxylase	-
ACODUA_RS16055 (ACODUA_16055)	pepP	3818348..3819658 (-)	1311	WP_014149719.1	Xaa-Pro aminopeptidase	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49343.51 Da
• Isoelectric Point: 6.1488

>NTDB_id=1111142 ACODUA_RS16035 WP_014149715.1 3813546..3814883(+) (pilR) [Methylotuvimicrobium alcaliphilum 20Z]
MKHPLTLVVDDEPDIRELLSITLKRMNIDTLCAENVDSARQLLQQHPFDLCLTDMKLPDGNGLELVEYLQSTGSTIPIAV
ITAHGNMDTAIKAMKAGAFDFISKPVDLPVLRQIVTKALQLAPDADTKERRTRHILLGESEPMRQVRSKIDKLARSQAPV
YISGESGSGKELVARLIHQQSPRSDKPFVAVNCGAIPPELMESEFFGHKKGSFSGAIADKKGLFQAAEGGTLFLDEVADL
PPSLQVKLLRAIQEKKVRAVGEQHETPVDVRILSATHKDLNQLVQEGVFRQDLYYRINVIDLNIPPLRERGNDIAQLAEH
ILASLNSNNAFQVRLSQSALTALKHYHFPGNVRELENILERAVALSDGKTIDADDLNLPINPEIVPDAPAFDPSKASLED
YLEDIERTAITIALENNRWNKTAAAKELGLSFRSLRYRLKKLGLD

Nucleotide

• Length: 1338 bp

>NTDB_id=1111142 ACODUA_RS16035 WP_014149715.1 3813546..3814883(+) (pilR) [Methylotuvimicrobium alcaliphilum 20Z]
ATGAAACACCCCTTGACTTTAGTCGTCGACGACGAGCCGGATATCCGAGAGCTGTTAAGCATTACGCTCAAACGCATGAA
CATCGACACCTTGTGCGCGGAAAATGTCGACTCGGCTCGGCAGTTGTTACAACAACATCCGTTCGATCTTTGCCTGACCG
ACATGAAGCTACCCGACGGCAACGGGCTCGAATTGGTCGAATACCTCCAAAGCACGGGCAGCACGATTCCGATTGCCGTA
ATTACCGCACACGGCAACATGGATACTGCGATCAAGGCAATGAAAGCCGGGGCCTTCGACTTTATCTCAAAACCGGTCGA
TTTACCGGTACTTCGGCAAATCGTCACGAAAGCCTTACAACTAGCCCCCGATGCCGATACCAAGGAAAGGCGCACACGAC
ATATTTTATTGGGCGAATCGGAGCCGATGCGCCAAGTCCGGTCTAAAATCGACAAGCTGGCACGTAGTCAGGCGCCTGTT
TATATCAGCGGCGAATCGGGGTCGGGTAAGGAATTGGTGGCGCGCTTGATTCATCAACAAAGCCCGCGTAGCGACAAGCC
TTTTGTTGCCGTAAACTGCGGCGCGATCCCGCCCGAACTTATGGAAAGCGAGTTTTTCGGACATAAAAAAGGCAGTTTCA
GCGGTGCAATTGCCGATAAAAAAGGTTTATTTCAAGCAGCCGAGGGCGGTACGCTATTTCTCGATGAAGTCGCCGATCTG
CCTCCTTCGCTGCAAGTCAAATTACTCCGCGCGATTCAGGAAAAAAAAGTACGCGCAGTCGGCGAACAACACGAAACACC
GGTCGATGTCCGCATCCTGAGCGCCACGCATAAAGATTTGAATCAATTGGTTCAGGAAGGGGTTTTTCGGCAAGATTTAT
ACTACCGGATCAATGTCATCGATCTCAATATTCCGCCGCTTCGCGAACGAGGCAATGATATCGCGCAACTAGCCGAACAT
ATTCTAGCCTCGTTAAATAGTAACAACGCTTTTCAAGTCCGGCTTTCGCAATCGGCGTTGACTGCATTGAAACATTATCA
TTTTCCGGGCAATGTTAGGGAGCTCGAGAATATTCTGGAGCGCGCCGTTGCGCTCAGCGACGGCAAAACGATCGATGCGG
ACGATTTAAATCTACCGATTAATCCGGAAATCGTCCCTGATGCGCCAGCGTTCGATCCGTCAAAAGCGTCGTTGGAAGAT
TATTTGGAAGATATCGAGCGAACCGCCATTACCATCGCACTCGAAAATAACCGATGGAATAAAACCGCAGCAGCAAAAGA
GCTGGGGTTATCGTTCCGATCATTGCGTTACCGGTTAAAAAAACTGGGCTTGGACTAG

Domains

Predicted by InterproScan.

• Sigma-54 interaction domain (Sigma54_activat) (136-302)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

• Response regulator receiver domain (Response_reg) (7-115)

3D structure

• AlphaFold DB: G4T4E7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	64.126	100	0.643
pilR	Acinetobacter baumannii strain A118	52.155	100	0.544
luxO	Vibrio cholerae strain A1552	39.189	99.775	0.391