Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ACNR93_RS02435 Genome accession   NZ_CP184736
Coordinates   466078..467376 (+) Length   432 a.a.
NCBI ID   WP_420543814.1    Uniprot ID   -
Organism   Streptococcus equinus strain NM-2-29     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 461078..472376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNR93_RS02410 (ACNR93_02410) - 461772..462416 (+) 645 WP_024344653.1 response regulator transcription factor -
  ACNR93_RS02415 (ACNR93_02415) - 462540..463940 (+) 1401 WP_029876003.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ACNR93_RS02420 (ACNR93_02420) - 463940..464296 (+) 357 WP_027968108.1 S1 RNA-binding domain-containing protein -
  ACNR93_RS02425 (ACNR93_02425) cysK 464370..465299 (-) 930 WP_420543812.1 cysteine synthase A -
  ACNR93_RS02430 (ACNR93_02430) - 465397..466023 (-) 627 WP_420543813.1 YigZ family protein -
  ACNR93_RS02435 (ACNR93_02435) comFA/cflA 466078..467376 (+) 1299 WP_420543814.1 DEAD/DEAH box helicase Machinery gene
  ACNR93_RS02440 (ACNR93_02440) - 467376..468041 (+) 666 WP_420543815.1 ComF family protein -
  ACNR93_RS02445 (ACNR93_02445) hpf 468118..468666 (+) 549 WP_024344660.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49186.26 Da        Isoelectric Point: 9.3219

>NTDB_id=1110938 ACNR93_RS02435 WP_420543814.1 466078..467376(+) (comFA/cflA) [Streptococcus equinus strain NM-2-29]
MEDKNDYYGRIFVESQLSDELKEEAEKLSSMVKRKDNFTCNRCGSLVLSENMLQTGQTYCRECLVFGRNISDSYLYYFPQ
KAFQKNNCLNWQGKLTLYQNEVSEGMLSGIAEKKDLLVHAVTGAGKTEMIYQSVAKTIDDGGCVCLASPRIDVCLELYKR
LSRDFSCPITLLHGDSEPYKRAPLIIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYQAVNQSLNPDGVKIFLTATST
DELDKKVRKGELKKLHLARRFHANPLVVPKMRWLGGLLKLMNKGKIPQKLDLLLKSQRKTGYPLLIFFPNIEQGKRFSMI
LQEKFPTEKVGFVSSQTEDRLELVEKFRRGEITILVSTTILERGVTFPCVDVFVVLANHKLYTKSALVQISGRVGRASER
PTGELLFLHDGVTKSMQKAIKEIKEMNKKGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1110938 ACNR93_RS02435 WP_420543814.1 466078..467376(+) (comFA/cflA) [Streptococcus equinus strain NM-2-29]
ATGGAAGATAAAAATGACTATTATGGAAGAATTTTTGTTGAGTCTCAATTGTCTGATGAGTTAAAAGAAGAAGCTGAAAA
ACTTTCTTCTATGGTAAAAAGAAAAGACAATTTTACGTGTAACCGTTGCGGGAGTCTTGTTTTATCAGAGAATATGCTAC
AAACTGGTCAGACTTACTGCAGAGAATGTCTAGTTTTTGGTCGTAATATCAGTGATTCTTATCTATACTATTTCCCGCAG
AAAGCATTTCAAAAAAATAATTGTCTAAATTGGCAAGGAAAATTAACACTTTATCAAAATGAAGTATCAGAAGGTATGTT
GTCGGGAATCGCTGAAAAGAAAGACTTATTAGTCCATGCGGTGACCGGGGCTGGCAAGACAGAAATGATTTATCAATCAG
TAGCAAAAACAATTGATGACGGTGGTTGTGTTTGTCTTGCTAGCCCACGAATTGATGTCTGTTTAGAACTTTATAAACGT
TTGTCTCGTGATTTTTCGTGTCCGATTACTTTGTTACACGGAGATTCTGAGCCTTATAAACGAGCACCATTAATTATTGC
TACTACTCATCAGCTTTTGAAATTCTATCGAGCATTTGACTTATTAATCATTGACGAAGTAGATGCCTTTCCATTTGTTG
ATAATAAAATGCTTTATCAAGCTGTGAATCAATCTTTGAACCCTGATGGCGTCAAAATATTTTTAACAGCTACATCGACA
GATGAATTAGATAAAAAAGTTCGAAAAGGTGAATTAAAAAAATTGCACTTAGCCAGACGTTTCCATGCAAATCCATTAGT
TGTCCCTAAAATGAGATGGCTTGGCGGGCTACTAAAGTTGATGAACAAAGGAAAAATACCCCAAAAGTTAGATTTACTTC
TTAAAAGTCAAAGGAAAACAGGCTATCCCCTACTAATCTTTTTTCCAAATATTGAGCAAGGAAAAAGATTTTCAATGATT
TTACAAGAAAAATTTCCTACTGAAAAGGTTGGTTTTGTGTCAAGTCAGACCGAAGATAGGCTTGAATTAGTTGAAAAATT
TAGAAGGGGCGAAATAACAATCCTAGTTAGCACAACCATCTTAGAACGTGGAGTTACCTTCCCTTGTGTTGACGTATTTG
TCGTATTAGCAAATCACAAACTATACACCAAGAGCGCTTTAGTGCAAATTTCTGGTCGTGTCGGAAGAGCTTCTGAACGA
CCTACAGGCGAATTATTATTCTTGCATGACGGTGTTACAAAATCCATGCAAAAAGCGATTAAAGAAATAAAAGAGATGAA
CAAGAAAGGAGGATTTTAA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(99-244)

Helicase conserved C-terminal domain (Helicase_C)

(292-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

63.232

98.843

0.625
  comFA/cflA Streptococcus pneumoniae D39

63.232

98.843

0.625
  comFA/cflA Streptococcus pneumoniae R6

63.232

98.843

0.625
  comFA/cflA Streptococcus pneumoniae TIGR4

63.232

98.843

0.625
  comFA/cflA Streptococcus mitis NCTC 12261

61.343

100

0.613
  comFA/cflA Streptococcus mitis SK321

61.343

100

0.613
  comFA Lactococcus lactis subsp. cremoris KW2

49.052

97.685

0.479
  comFA Bacillus subtilis subsp. subtilis str. 168

36.782

100

0.37

Multiple sequence alignment