Detailed information NTG1106888

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: ACLKM6_RS05040
• Genome accession: NZ_CP183890
• Coordinates: 1057646..1058350 (-)
• Length: 234 a.a.
• NCBI ID: WP_005177031.1
• Uniprot ID: A0A6C0Y3U4
• Organism: Acinetobacter indicus strain D11_NDM_tet(X5)
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1052646..1063350

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLKM6_RS05015	-	1052760..1054079 (+)	1320	WP_005177019.1	adenylosuccinate synthase	-
ACLKM6_RS05020	-	1054216..1055001 (+)	786	WP_168395100.1	M48 family metallopeptidase	-
ACLKM6_RS05025	-	1055090..1055398 (+)	309	WP_005177024.1	hypothetical protein	-
ACLKM6_RS05030	-	1055561..1056343 (+)	783	WP_005177027.1	M48 family metallopeptidase	-
ACLKM6_RS05035	-	1056426..1057475 (-)	1050	WP_411686968.1	NADP(H)-dependent aldo-keto reductase	-
ACLKM6_RS05040	crp	1057646..1058350 (-)	705	WP_005177031.1	cAMP-activated global transcriptional regulator CRP	Regulator
ACLKM6_RS05045	-	1058498..1058920 (+)	423	WP_005177032.1	OsmC family protein	-
ACLKM6_RS05050	clpB	1059245..1061824 (+)	2580	WP_160241448.1	ATP-dependent chaperone ClpB	-

Sequence

Protein

• Length: 234 a.a.
• Molecular weight: 26315.89 Da
• Isoelectric Point: 4.6470

>NTDB_id=1106888 ACLKM6_RS05040 WP_005177031.1 1057646..1058350(-) (crp) [Acinetobacter indicus strain D11_NDM_tet(X5)]
MTSNFSQLSTDALSPGQLPDSVKALLKRAYINRYPKRTTIVDAGSESKSLYLILKGSVSIILREDDDREIVVAYLNPGDF
FGEMGLFEANPQRTAEVRTRDVCEIAEVTYENFHELSKQYPDLSYAVFAQLVRRLKNTTRKVTDLAFIDVSGRIARCLID
LSAQPEAMILPNGRQIRITRQEIGRIVGCSREMVGRVLKTLEEQGMIETDGKAILIFDASLEQNDAADEQFDDE

Nucleotide

• Length: 705 bp

>NTDB_id=1106888 ACLKM6_RS05040 WP_005177031.1 1057646..1058350(-) (crp) [Acinetobacter indicus strain D11_NDM_tet(X5)]
ATGACTTCAAACTTTTCACAATTAAGCACCGATGCCCTGTCTCCTGGTCAATTACCAGATTCAGTCAAGGCATTATTAAA
ACGTGCATATATCAACCGTTATCCGAAACGGACCACAATTGTTGATGCGGGGTCTGAATCAAAATCACTTTATTTGATTC
TGAAAGGATCTGTTTCCATCATTCTGCGTGAAGATGATGATCGCGAAATTGTTGTGGCGTATTTGAATCCGGGTGACTTC
TTTGGGGAAATGGGTCTATTCGAAGCAAATCCACAACGTACTGCAGAAGTACGCACACGTGACGTTTGTGAAATTGCCGA
AGTGACTTATGAAAACTTCCACGAGCTCAGCAAGCAATATCCAGATTTAAGCTATGCGGTATTTGCCCAACTGGTGCGCC
GTTTAAAAAATACCACGCGTAAAGTGACCGATCTGGCCTTCATTGATGTTTCAGGCCGTATTGCGCGTTGTCTGATTGAC
CTGTCTGCGCAGCCTGAAGCCATGATTTTGCCAAATGGCCGTCAAATCCGCATTACCCGTCAGGAAATTGGCCGCATTGT
TGGCTGTTCACGTGAAATGGTCGGCCGTGTTCTGAAAACACTGGAAGAACAAGGCATGATCGAAACTGATGGTAAAGCCA
TTCTGATTTTTGATGCCTCTTTAGAGCAAAATGATGCAGCAGATGAACAGTTTGATGATGAATAA

Domains

Predicted by InterproScan.

• Cyclic nucleotide-binding domain (cNMP_binding) (33-120)

• Bacterial regulatory proteins, crp family (Crp) (176-207)

3D structure

• AlphaFold DB: A0A6C0Y3U4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Acinetobacter baumannii D1279779	91.026	100	0.91
crp	Vibrio cholerae strain A1552	46.829	87.607	0.41
crp	Haemophilus influenzae Rd KW20	47.179	83.333	0.393