Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   V3C22_RS08575 Genome accession   NZ_CP183775
Coordinates   1746881..1748200 (-) Length   439 a.a.
NCBI ID   WP_226706881.1    Uniprot ID   -
Organism   Streptococcus mutans strain Xc     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1741881..1753200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V3C22_RS08540 (V3C22_08540) - 1742667..1742942 (-) 276 WP_002284750.1 Blp family class II bacteriocin -
  V3C22_RS08545 (V3C22_08545) - 1743246..1743380 (-) 135 WP_080062158.1 hypothetical protein -
  V3C22_RS08550 (V3C22_08550) - 1743838..1743999 (-) 162 WP_002295609.1 hypothetical protein -
  V3C22_RS08555 (V3C22_08555) - 1744244..1745272 (-) 1029 WP_002295608.1 thioredoxin family protein -
  V3C22_RS08560 (V3C22_08560) - 1745756..1745944 (-) 189 WP_002284747.1 Blp family class II bacteriocin -
  V3C22_RS08565 (V3C22_08565) - 1746108..1746321 (-) 214 Protein_1639 Blp family class II bacteriocin -
  V3C22_RS08570 (V3C22_08570) comC/blpC 1746588..1746728 (+) 141 WP_002270250.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  V3C22_RS08575 (V3C22_08575) comD/blpH 1746881..1748200 (-) 1320 WP_226706881.1 GHKL domain-containing protein Regulator
  V3C22_RS08580 (V3C22_08580) comE/blpR 1748197..1748949 (-) 753 WP_002265454.1 response regulator transcription factor Regulator
  V3C22_RS08585 (V3C22_08585) - 1749414..1750052 (-) 639 WP_002267938.1 VTT domain-containing protein -
  V3C22_RS08590 (V3C22_08590) - 1750100..1750726 (-) 627 WP_002268642.1 hypothetical protein -
  V3C22_RS08595 (V3C22_08595) der 1750801..1752111 (-) 1311 WP_002262117.1 ribosome biogenesis GTPase Der -
  V3C22_RS08600 (V3C22_08600) dnaI 1752124..1753023 (-) 900 WP_002284744.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50304.47 Da        Isoelectric Point: 9.8775

>NTDB_id=1105965 V3C22_RS08575 WP_226706881.1 1746881..1748200(-) (comD/blpH) [Streptococcus mutans strain Xc]
MNEALMILLNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIALSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDRNQGIVMGSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQALYVIESYNVIPTLKFRKFVVIVYLILFLILISFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSGKIQLPDMELLDFITILSILCDNAIEAALESLKPEIQLAFFKKNGSIVFIIQNSSKEKQIDVSKIFKENYS
TKGSNRGIGLAKVNHILEHYPKTSLQTSSHHHLFKQLLI

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=1105965 V3C22_RS08575 WP_226706881.1 1746881..1748200(-) (comD/blpH) [Streptococcus mutans strain Xc]
ATGAATGAAGCCTTAATGATACTTTTAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCCAA
GGTAAGTAATGTTACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTGAACGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGCTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATAGAAATCAAGGAATTGTAATGGGCAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTAAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATCCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAAGCATTGTATGTTATAGAGAGTTATAATGTGATACC
GACTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGATCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATCACCCAGTATAGTCAGCAAATA
GAATCTCTTTACAAGGATATTCGAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGCCATCTAGCTAATATTCAAAACGATGCTGTCAAGGGTATCTTATCAGCAAAAATCTTAGAAGCTCAAAATAAA
AAAATTGCTGTCAATGTAGAGGTCTCAGGTAAAATACAGCTGCCTGATATGGAGTTGCTTGATTTTATTACTATACTTTC
TATCTTGTGCGATAATGCTATTGAGGCCGCTCTCGAATCACTAAAACCTGAAATTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGCATAGTCTTTATCATCCAGAATTCCTCCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACCAGTTTACAAAC
AAGCAGTCATCATCATTTATTCAAGCAACTCCTAATCTAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(337-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

97.722

100

0.977

Multiple sequence alignment