Detailed information NTG0110588

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACAM36_RS23995
• Genome accession: NZ_AP031604
• Coordinates: 5178743..5180080 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa isolate PaSz
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5173743..5185080

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM36_RS23970 (RVB5_47570)	pgeF	5173886..5174614 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
ACAM36_RS23975 (RVB5_47580)	rluD	5174611..5175573 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACAM36_RS23980 (RVB5_47590)	-	5175719..5176744 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACAM36_RS23985 (RVB5_47600)	-	5176901..5177146 (+)	246	WP_003102591.1	PP0621 family protein	-
ACAM36_RS23990 (RVB5_47610)	pilS	5177136..5178728 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
ACAM36_RS23995 (RVB5_47620)	pilR	5178743..5180080 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACAM36_RS24000 (RVB5_47630)	thiO	5180126..5181220 (-)	1095	WP_023084775.1	glycine oxidase ThiO	-
ACAM36_RS24005 (RVB5_47640)	-	5181355..5181864 (+)	510	WP_034037343.1	Tfp pilus assembly protein FimT/FimU	-
ACAM36_RS24010 (RVB5_47650)	-	5181970..5182476 (+)	507	WP_003094696.1	Tfp pilus assembly protein FimT/FimU	-
ACAM36_RS24015 (RVB5_47660)	pilV	5182467..5183024 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ACAM36_RS24020 (RVB5_47670)	pilW	5183021..5183845 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ACAM36_RS24025 (RVB5_47680)	pilX	5183842..5184429 (+)	588	WP_059297987.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=110588 ACAM36_RS23995 WP_003094694.1 5178743..5180080(+) (pilR) [Pseudomonas aeruginosa isolate PaSz]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=110588 ACAM36_RS23995 WP_003094694.1 5178743..5180080(+) (pilR) [Pseudomonas aeruginosa isolate PaSz]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTTGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAACTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGTGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384