Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACM591_RS05895 Genome accession   NZ_CP183486
Coordinates   1309130..1309759 (+) Length   209 a.a.
NCBI ID   WP_017723494.1    Uniprot ID   -
Organism   Staphylococcus sp. Ze2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1304130..1314759
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM591_RS05870 (ACM591_05870) - 1304976..1305962 (-) 987 WP_029378976.1 FUSC family protein -
  ACM591_RS05875 (ACM591_05875) map 1306139..1306891 (+) 753 WP_029378977.1 type I methionyl aminopeptidase -
  ACM591_RS05880 (ACM591_05880) - 1306996..1307382 (+) 387 WP_326026239.1 hypothetical protein -
  ACM591_RS05885 (ACM591_05885) liaF 1307399..1308100 (+) 702 WP_029378979.1 cell wall-active antibiotics response protein LiaF -
  ACM591_RS05890 (ACM591_05890) vraS 1308097..1309140 (+) 1044 WP_029378980.1 sensor histidine kinase Regulator
  ACM591_RS05895 (ACM591_05895) vraR 1309130..1309759 (+) 630 WP_017723494.1 response regulator transcription factor Regulator
  ACM591_RS05900 (ACM591_05900) - 1310028..1311173 (-) 1146 WP_029378981.1 YihY/virulence factor BrkB family protein -
  ACM591_RS05905 (ACM591_05905) - 1311529..1311813 (-) 285 WP_029378982.1 hypothetical protein -
  ACM591_RS05910 (ACM591_05910) - 1311820..1312284 (-) 465 WP_326026237.1 low molecular weight protein-tyrosine-phosphatase -
  ACM591_RS05915 (ACM591_05915) - 1312419..1312622 (+) 204 WP_017723498.1 DUF1128 family protein -
  ACM591_RS05920 (ACM591_05920) - 1312640..1313878 (+) 1239 WP_326026905.1 aminopeptidase -
  ACM591_RS05925 (ACM591_05925) - 1313966..1314487 (+) 522 WP_029378985.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23734.27 Da        Isoelectric Point: 4.7778

>NTDB_id=1105866 ACM591_RS05895 WP_017723494.1 1309130..1309759(+) (vraR) [Staphylococcus sp. Ze2]
MPIKVLFVDDHEMVRIGISSYLSTQPDIDVVGEGKSGKEAIEKAHQLNPDLILMDLLMDDMDGVEATEQVKKDLPHMKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNNESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1105866 ACM591_RS05895 WP_017723494.1 1309130..1309759(+) (vraR) [Staphylococcus sp. Ze2]
ATGCCGATTAAAGTTTTATTTGTGGATGACCATGAAATGGTCCGAATTGGAATATCTAGCTATTTATCAACACAACCAGA
TATTGATGTTGTAGGAGAAGGGAAATCGGGAAAGGAAGCAATTGAAAAAGCTCACCAATTGAATCCTGATTTAATATTAA
TGGATTTACTAATGGATGATATGGACGGTGTTGAAGCAACCGAACAAGTAAAAAAAGATTTACCTCATATGAAAGTAGTC
ATGCTTACGAGTTATATAGAAGATAACGAAGTATACCGTGCACTTGATTCTGGTGTGGATAGCTACATTTTAAAAACAAC
GAGTGCTAGTGATATTGCAGAGGCAATAAGAAAAACCTATAATAATGAGTCGGTTTTTGAAGCAGAAGTTTTAGTTAAGA
TGAGAAATAGAATGAAGCAACGTGCAGAATTATATGAAATGTTAACAGAACGTGAGATGGAAATCTTATTATTAATAGCA
AAAGGCTACTCAAACCAAGAAATAGCAAGCGCCTCACATATAACAATTAAAACTGTTAAAACACATGTAAGTAATATTTT
GAGTAAATTAGAAGTACAAGATAGAACACAAGCTGTTATTTACGCTTTTCAACATAACTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.517

100

0.885
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment