Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACNVED_RS10490 Genome accession   NZ_CP183303
Coordinates   2427392..2428051 (-) Length   219 a.a.
NCBI ID   WP_419418969.1    Uniprot ID   -
Organism   Legionella sp. D16C41     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2422392..2433051
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNVED_RS10475 (ACNVED_10475) - 2423819..2424385 (-) 567 WP_419418966.1 endopeptidase IV -
  ACNVED_RS10480 (ACNVED_10480) - 2424382..2425104 (-) 723 WP_419418967.1 L,D-transpeptidase -
  ACNVED_RS10485 (ACNVED_10485) uvrC 2425399..2427240 (-) 1842 WP_419418968.1 excinuclease ABC subunit UvrC -
  ACNVED_RS10490 (ACNVED_10490) letA 2427392..2428051 (-) 660 WP_419418969.1 two-component system response regulator LetA Regulator
  ACNVED_RS10495 (ACNVED_10495) - 2428236..2428364 (-) 129 WP_419418970.1 hypothetical protein -
  ACNVED_RS10500 (ACNVED_10500) phhA 2428538..2429356 (-) 819 WP_419418971.1 phenylalanine 4-monooxygenase -
  ACNVED_RS10505 (ACNVED_10505) bioC 2429601..2430458 (-) 858 WP_419421175.1 malonyl-ACP O-methyltransferase BioC -
  ACNVED_RS10510 (ACNVED_10510) - 2430460..2431206 (+) 747 WP_419418972.1 ComF family protein -
  ACNVED_RS10515 (ACNVED_10515) - 2431352..2432422 (-) 1071 WP_419418973.1 M50 family metallopeptidase -
  ACNVED_RS10520 (ACNVED_10520) - 2432589..2432867 (-) 279 WP_419418974.1 hypothetical protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24305.69 Da        Isoelectric Point: 6.8776

>NTDB_id=1105181 ACNVED_RS10490 WP_419418969.1 2427392..2428051(-) (letA) [Legionella sp. D16C41]
MIKILIVDDHALVRMGIRRLLEDLPDMDVVAEAASGEEALLLVKSHKPDVLLLDMKMPGIDGWEVTRRLKKSNPHIRIIA
VTAICADPLPTRVLQLGAMGYLTKESGVQEMAAAIRKVAKGEKYLSAEIAQKMAINSLMAVQGSPFNALSEREMQVMLMI
TSGMTVQDIADRLFLSTKTINGYRYRIFEKLGIKNDVELTYLAMKHGVIEKPSDALLDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1105181 ACNVED_RS10490 WP_419418969.1 2427392..2428051(-) (letA) [Legionella sp. D16C41]
TTGATCAAAATACTCATTGTCGATGACCATGCATTGGTTAGAATGGGTATTCGCCGACTTTTAGAAGATTTGCCTGATAT
GGATGTAGTTGCTGAGGCTGCAAGCGGCGAGGAAGCCCTATTGTTGGTGAAATCTCACAAACCTGATGTTCTTCTATTGG
ATATGAAAATGCCAGGTATTGATGGATGGGAAGTCACGCGGCGACTTAAAAAATCTAATCCTCATATCAGGATTATTGCT
GTTACAGCAATTTGTGCTGATCCCTTACCCACTCGTGTTTTACAGTTAGGCGCTATGGGTTATCTCACTAAAGAATCTGG
CGTGCAAGAAATGGCTGCAGCTATTCGCAAAGTAGCAAAGGGTGAGAAGTATTTAAGTGCTGAAATTGCTCAGAAGATGG
CTATTAATAGTTTAATGGCTGTTCAAGGCTCACCATTTAATGCTTTATCAGAGCGAGAAATGCAGGTTATGTTAATGATT
ACTAGTGGGATGACAGTACAAGATATCGCTGATCGTCTATTTTTAAGCACTAAGACTATTAATGGTTATCGTTATCGAAT
TTTTGAGAAGTTAGGTATTAAAAATGATGTTGAATTAACCTATCTTGCTATGAAGCATGGTGTGATTGAAAAGCCATCTG
ACGCACTCCTAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

84.018

100

0.84
  letA Legionella pneumophila strain ERS1305867

84.018

100

0.84

Multiple sequence alignment