Detailed information NTG1102772

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: ACLM40_RS09510
• Genome accession: NZ_CP182859
• Coordinates: 2027960..2028616 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain APPFJLYC01
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2022960..2033616

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLM40_RS09490 (ACLM40_09490)	nanA	2023333..2024211 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
ACLM40_RS09495 (ACLM40_09495)	nagB	2024261..2025064 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
ACLM40_RS09500 (ACLM40_09500)	nagA	2025116..2026261 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
ACLM40_RS09505 (ACLM40_09505)	fumC	2026411..2027805 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
ACLM40_RS09510 (ACLM40_09510)	sxy/tfoX	2027960..2028616 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
ACLM40_RS09515 (ACLM40_09515)	rpsJ	2029024..2029335 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
ACLM40_RS09520 (ACLM40_09520)	rplC	2029361..2029987 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
ACLM40_RS09525 (ACLM40_09525)	rplD	2030003..2030605 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
ACLM40_RS09530 (ACLM40_09530)	rplW	2030602..2030907 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
ACLM40_RS09535 (ACLM40_09535)	rplB	2030928..2031749 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
ACLM40_RS09540 (ACLM40_09540)	rpsS	2031777..2032052 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
ACLM40_RS09545 (ACLM40_09545)	rplV	2032063..2032395 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
ACLM40_RS09550 (ACLM40_09550)	rpsC	2032414..2033121 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
ACLM40_RS09555 (ACLM40_09555)	rplP	2033135..2033545 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=1102772 ACLM40_RS09510 WP_005609196.1 2027960..2028616(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain APPFJLYC01]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=1102772 ACLM40_RS09510 WP_005609196.1 2027960..2028616(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain APPFJLYC01]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376