Detailed information NTG0109799

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: ABXG87_RS05390
• Genome accession: NZ_AP031488
• Coordinates: 1183592..1184299 (-)
• Length: 235 a.a.
• NCBI ID: WP_002884978.1
• Uniprot ID: A0AB33ZBK5
• Organism: Streptococcus salivarius strain NBRC 13956
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1178592..1189299

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABXG87_RS05365 (Ssa13956_10030)	-	1179260..1180474 (+)	1215	WP_004182608.1	aminoacyltransferase	-
ABXG87_RS05370	-	1180576..1180852 (-)	277	Protein_1004	ISL3 family transposase	-
ABXG87_RS05375 (Ssa13956_10040)	-	1181023..1181382 (-)	360	WP_045769141.1	YbaN family protein	-
ABXG87_RS05380 (Ssa13956_10050)	vicX	1181441..1182253 (-)	813	WP_013990680.1	MBL fold metallo-hydrolase	Regulator
ABXG87_RS05385 (Ssa13956_10060)	vicK	1182259..1183599 (-)	1341	WP_002885062.1	cell wall metabolism sensor histidine kinase VicK	Regulator
ABXG87_RS05390 (Ssa13956_10070)	vicR	1183592..1184299 (-)	708	WP_002884978.1	response regulator YycF	Regulator
ABXG87_RS05395 (Ssa13956_10080)	-	1184584..1185351 (+)	768	WP_038675884.1	amino acid ABC transporter ATP-binding protein	-
ABXG87_RS05400 (Ssa13956_10090)	-	1185361..1186194 (+)	834	WP_013990682.1	transporter substrate-binding domain-containing protein	-
ABXG87_RS05405 (Ssa13956_10100)	-	1186212..1186910 (+)	699	WP_002886251.1	amino acid ABC transporter permease	-
ABXG87_RS05410 (Ssa13956_10110)	-	1186922..1187572 (+)	651	WP_045769140.1	amino acid ABC transporter permease	-
ABXG87_RS05415 (Ssa13956_10120)	-	1187760..1188527 (+)	768	WP_002885036.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27045.90 Da
• Isoelectric Point: 4.8387

>NTDB_id=109799 ABXG87_RS05390 WP_002884978.1 1183592..1184299(-) (vicR) [Streptococcus salivarius strain NBRC 13956]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=109799 ABXG87_RS05390 WP_002884978.1 1183592..1184299(-) (vicR) [Streptococcus salivarius strain NBRC 13956]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCGATTTCGGATATCATCAAGTTTAATCTAACTAAAGAAGGTTATGA
AGTGGTTACAGCCTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCGATTATCATGCTTTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.687	99.149	0.8
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.559	100	0.387