Detailed information NTG1097989

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: RBI96_RS16990
• Genome accession: NZ_CP181075
• Coordinates: 3598805..3600142 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain LACPHL-BACT-2023-00013
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 3593805..3605142

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RBI96_RS16965 (RBI96_016965)	pgeF	3593948..3594676 (-)	729	WP_003094684.1	peptidoglycan editing factor PgeF	-
RBI96_RS16970 (RBI96_016970)	rluD	3594673..3595635 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
RBI96_RS16975 (RBI96_016975)	-	3595781..3596806 (+)	1026	WP_003094687.1	outer membrane protein assembly factor BamD	-
RBI96_RS16980 (RBI96_016980)	-	3596963..3597208 (+)	246	WP_014603563.1	PP0621 family protein	-
RBI96_RS16985 (RBI96_016985)	pilS	3597198..3598790 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
RBI96_RS16990 (RBI96_016990)	pilR	3598805..3600142 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
RBI96_RS16995 (RBI96_016995)	thiO	3600188..3601282 (-)	1095	WP_003094695.1	glycine oxidase ThiO	-
RBI96_RS17000 (RBI96_017000)	-	3601417..3601926 (+)	510	WP_015503652.1	GspH/FimT family pseudopilin	-
RBI96_RS17005 (RBI96_017005)	-	3602032..3602538 (+)	507	WP_003094696.1	GspH/FimT family pseudopilin	-
RBI96_RS17010 (RBI96_017010)	pilV	3602529..3603086 (+)	558	WP_003094697.1	type 4a pilus minor pilin PilV	Machinery gene
RBI96_RS17015 (RBI96_017015)	pilW	3603083..3603907 (+)	825	WP_003094698.1	type 4a pilus minor pilin PilW	-
RBI96_RS17020 (RBI96_017020)	pilX	3603904..3604491 (+)	588	WP_003094700.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1097989 RBI96_RS16990 WP_003094694.1 3598805..3600142(+) (pilR) [Pseudomonas aeruginosa strain LACPHL-BACT-2023-00013]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1097989 RBI96_RS16990 WP_003094694.1 3598805..3600142(+) (pilR) [Pseudomonas aeruginosa strain LACPHL-BACT-2023-00013]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTAGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384