Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABWV75_RS04800 Genome accession   NZ_AP031487
Coordinates   949255..949884 (+) Length   209 a.a.
NCBI ID   WP_002450048.1    Uniprot ID   A0A1L8Y4G9
Organism   Staphylococcus hominis subsp. novobiosepticus strain NBRC 113928     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 944255..954884
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABWV75_RS04775 (SKB0068_09400) map 945072..945824 (+) 753 WP_002450057.1 type I methionyl aminopeptidase -
  ABWV75_RS04780 (SKB0068_09410) - 945873..946883 (-) 1011 WP_087436993.1 HoxN/HupN/NixA family nickel/cobalt transporter -
  ABWV75_RS04785 (SKB0068_09420) - 947114..947500 (+) 387 WP_087436992.1 hypothetical protein -
  ABWV75_RS04790 (SKB0068_09430) liaF 947521..948222 (+) 702 WP_087436991.1 cell wall-active antibiotics response protein LiaF -
  ABWV75_RS04795 (SKB0068_09440) vraS 948219..949253 (+) 1035 WP_049415634.1 sensor histidine kinase Regulator
  ABWV75_RS04800 (SKB0068_09450) vraR 949255..949884 (+) 630 WP_002450048.1 two-component system response regulator VraR Regulator
  ABWV75_RS04805 (SKB0068_09460) - 949964..951172 (-) 1209 WP_242267842.1 YihY/virulence factor BrkB family protein -
  ABWV75_RS04810 (SKB0068_09470) - 951264..951545 (-) 282 WP_002450075.1 hypothetical protein -
  ABWV75_RS04815 (SKB0068_09480) - 951551..952015 (-) 465 WP_002455129.1 low molecular weight protein-tyrosine-phosphatase -
  ABWV75_RS04820 (SKB0068_09490) - 952157..952363 (+) 207 WP_353318732.1 DUF1128 domain-containing protein -
  ABWV75_RS04825 (SKB0068_09500) - 952375..953622 (+) 1248 WP_353318733.1 aminopeptidase -
  ABWV75_RS04830 (SKB0068_09510) - 953655..954188 (+) 534 WP_087436988.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23592.26 Da        Isoelectric Point: 5.3673

>NTDB_id=109738 ABWV75_RS04800 WP_002450048.1 949255..949884(+) (vraR) [Staphylococcus hominis subsp. novobiosepticus strain NBRC 113928]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGSSGKEAIEKAHTLNPDLILMDLLMNDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYRGESVFEPEVLVKMRNRMKKKAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=109738 ABWV75_RS04800 WP_002450048.1 949255..949884(+) (vraR) [Staphylococcus hominis subsp. novobiosepticus strain NBRC 113928]
ATGACGATTAAAGTATTATTTGTAGATGATCATGAAATGGTTAGAATTGGTATTTCAAGTTATTTATCTACTCAATCTGA
TATTGAAGTAGTAGGGGAAGGATCATCAGGAAAAGAGGCAATTGAAAAAGCACATACGTTAAATCCTGATTTAATTTTAA
TGGATTTGTTAATGAATGATATGGACGGTGTAGAAGCGACGACACAAATAAAAAAAGATTTGCCTCACATCAAAGTAGTC
ATGTTAACAAGTTTTATAGAAGATAAAGAAGTATATAGGGCACTTGATGCAGGGGTTGATAGTTATATATTAAAAACGAC
AAGTGCAAGTGATATTGCAGAAGCAGTTAGAAAAACATATCGTGGAGAATCTGTATTTGAGCCAGAAGTTTTAGTAAAAA
TGAGAAATAGAATGAAGAAGAAAGCAGAATTATATGAAATGCTCACTGAACGTGAAATGGAAATATTGTTATTAATTGCT
AAAGGCTATTCTAATCAAGAAATTGCCAGTGCTTCACATATTACAATTAAAACAGTAAAAACACATGTGAGTAATATTTT
AAGTAAACTAGAGGTACAAGATAGAACACAAGCGGTTATTTATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L8Y4G9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment