Detailed information NTG0109729

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: ABWV75_RS00315
• Genome accession: NZ_AP031487
• Coordinates: 64290..65651 (-)
• Length: 453 a.a.
• NCBI ID: WP_353318195.1
• Uniprot ID: -
• Organism: Staphylococcus hominis subsp. novobiosepticus strain NBRC 113928
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	41213..64293	64290..65651	flank	-3

Gene organization within MGE regions

Location: 41213..65651

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABWV75_RS00205 (SKB0068_00380)	-	41213..42892 (+)	1680	WP_336942606.1	recombinase family protein	-
ABWV75_RS00210 (SKB0068_00390)	-	42981..43319 (+)	339	WP_017175172.1	SAUGI family uracil-DNA glycosylase inhibitor	-
ABWV75_RS00215 (SKB0068_00400)	-	43413..43724 (+)	312	WP_311045603.1	DUF960 family protein	-
ABWV75_RS00220 (SKB0068_00410)	-	43739..44236 (+)	498	WP_017175170.1	DUF1643 domain-containing protein	-
ABWV75_RS00225 (SKB0068_00420)	-	44250..44471 (+)	222	WP_017175169.1	hypothetical protein	-
ABWV75_RS00230 (SKB0068_00430)	-	44656..45471 (+)	816	WP_336942595.1	hypothetical protein	-
ABWV75_RS00235 (SKB0068_00440)	-	45906..49025 (-)	3120	WP_353318170.1	type I restriction endonuclease subunit R	-
ABWV75_RS00240 (SKB0068_00450)	-	49009..50262 (-)	1254	WP_353318171.1	restriction endonuclease subunit S	-
ABWV75_RS00245 (SKB0068_00460)	-	50252..51766 (-)	1515	WP_353318173.1	class I SAM-dependent DNA methyltransferase	-
ABWV75_RS00250 (SKB0068_00470)	-	51901..52458 (+)	558	WP_353318175.1	hypothetical protein	-
ABWV75_RS00255 (SKB0068_00480)	-	52492..53817 (+)	1326	WP_353318177.1	SEFIR domain-containing protein	-
ABWV75_RS00260 (SKB0068_00490)	-	53952..55376 (+)	1425	WP_353318179.1	RyR domain-containing protein	-
ABWV75_RS00265 (SKB0068_00500)	-	55394..57331 (+)	1938	WP_353318180.1	TIR domain-containing protein	-
ABWV75_RS00270 (SKB0068_00510)	-	57571..58131 (+)	561	WP_353318182.1	hypothetical protein	-
ABWV75_RS00275 (SKB0068_00520)	-	58252..58395 (+)	144	WP_353318184.1	hypothetical protein	-
ABWV75_RS00280 (SKB0068_00530)	-	58388..59569 (+)	1182	WP_353318186.1	restriction endonuclease subunit S	-
ABWV75_RS00285 (SKB0068_00540)	-	59880..60377 (-)	498	WP_162194305.1	GNAT family N-acetyltransferase	-
ABWV75_RS00290	-	60655..60876 (-)	222	Protein_55	hypothetical protein	-
ABWV75_RS00295 (SKB0068_00550)	-	60891..61400 (-)	510	WP_353318187.1	DUF1643 domain-containing protein	-
ABWV75_RS00300 (SKB0068_00560)	-	61416..61727 (-)	312	WP_353318189.1	DUF960 family protein	-
ABWV75_RS00305 (SKB0068_00570)	-	61814..62164 (-)	351	WP_353318191.1	SAUGI family uracil-DNA glycosylase inhibitor	-
ABWV75_RS00310 (SKB0068_00580)	ccrB	62665..64293 (-)	1629	WP_353318193.1	recombinase family protein	Machinery gene
ABWV75_RS00315 (SKB0068_00590)	ccrA	64290..65651 (-)	1362	WP_353318195.1	recombinase family protein	Machinery gene

Sequence

Protein

• Length: 453 a.a.
• Molecular weight: 53089.94 Da
• Isoelectric Point: 9.8782

>NTDB_id=109729 ABWV75_RS00315 WP_353318195.1 64290..65651(-) (ccrA) [Staphylococcus hominis subsp. novobiosepticus strain NBRC 113928]
MEEAVAYVRQSTLKQQSLATQKSLILNTAKQYGWPNVKFYDDKRSGRNTKRSGYQKMVEMITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHVTIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTRNGIREKAKQGKLITTHAPFGYRYR
QGHFVVHEEEAYTVKAVYRWYLQGLGYKKISQHLDNNPKLTPRKPYQVRNILLNPNYCGRVINKYGTFNDLVPSIVDIDT
FEQAQQRRLNKHHKQHISENKLKKLLKCPYCQSTLTNLTIKKEHHSLRYYVCPKNMNEAYHTCPFKGINAQMIETEVLNT
CKAYCNNQSFHDKLNETILKALKRQQIKHRQSHLTQEQLIEKLAQNQIDIETFKHLSAGSESEERYSNYSHKQITKTIRH
IIKDKLTLETIAPLIDDITITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVT

Nucleotide

• Length: 1362 bp

>NTDB_id=109729 ABWV75_RS00315 WP_353318195.1 64290..65651(-) (ccrA) [Staphylococcus hominis subsp. novobiosepticus strain NBRC 113928]
ATGGAAGAAGCCGTTGCTTACGTACGTCAAAGTACACTAAAACAACAAAGTTTAGCGACTCAGAAATCTCTGATTTTAAA
TACTGCTAAGCAATATGGATGGCCTAATGTAAAGTTTTATGATGATAAGAGAAGCGGTCGAAATACGAAACGGTCGGGTT
ATCAAAAGATGGTAGAAATGATTACGTCCGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACGTCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGCTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGTGAAC
AGACACGAAATGGGATAAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCACCTTTTGGCTATCGTTATAGA
CAAGGTCATTTTGTTGTACATGAAGAAGAAGCGTATACAGTCAAAGCTGTCTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAAATTTCCCAACATTTAGATAACAATCCTAAGCTTACTCCACGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAGTATGGAACATTTAATGATTTAGTACCTTCTATTGTCGACATTGATACC
TTTGAACAAGCACAGCAACGTCGCTTGAATAAACATCATAAACAACACATTTCTGAAAACAAATTAAAGAAGCTACTTAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACAATAAAAAAAGAACATCATTCTCTACGTTACTATGTCTGTCCTA
AAAATATGAATGAAGCTTATCATACGTGTCCATTTAAAGGTATCAATGCGCAAATGATTGAAACAGAGGTCCTCAACACT
TGTAAAGCATATTGTAACAATCAGTCATTTCATGACAAATTAAATGAGACAATACTAAAAGCTCTAAAACGCCAACAAAT
AAAACACAGACAATCACATCTAACACAAGAACAACTCATCGAAAAGCTAGCACAAAATCAAATTGATATCGAGACGTTTA
AACATTTATCTGCTGGCTCTGAAAGTGAAGAACGTTATTCTAATTATTCACATAAACAAATTACCAAAACAATCCGTCAT
ATAATCAAAGATAAATTGACATTAGAAACCATAGCACCTTTGATTGATGACATTACAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAATAGTCCCCTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTCACAT
GA

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (168-248)

• Resolvase, N terminal domain (Resolvase) (4-147)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-321)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus COL	55.756	97.792	0.545
ccrA	Staphylococcus aureus N315	53.047	97.792	0.519