Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACLKMS_RS03930 Genome accession   NZ_CP180533
Coordinates   842093..842809 (-) Length   238 a.a.
NCBI ID   WP_001829999.1    Uniprot ID   C0LF82
Organism   Staphylococcus epidermidis strain BP21     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 837093..847809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLKMS_RS03915 (ACLKMS_03915) - 838374..839327 (+) 954 WP_002503805.1 LacI family DNA-binding transcriptional regulator -
  ACLKMS_RS03920 (ACLKMS_03920) - 839587..841059 (+) 1473 WP_001830011.1 sucrose-6-phosphate hydrolase -
  ACLKMS_RS03925 (ACLKMS_03925) - 841066..842025 (+) 960 WP_049377025.1 carbohydrate kinase family protein -
  ACLKMS_RS03930 (ACLKMS_03930) agrA 842093..842809 (-) 717 WP_001829999.1 quorum-sensing response regulator AgrA Regulator
  ACLKMS_RS03935 (ACLKMS_03935) agrC 842826..844115 (-) 1290 WP_002494641.1 quorum-sensing sensor histidine kinase AgrC -
  ACLKMS_RS03940 (ACLKMS_03940) agrD 844140..844280 (-) 141 WP_002468352.1 cyclic lactone autoinducer peptide AgrD -
  ACLKMS_RS03945 (ACLKMS_03945) - 844286..844849 (-) 564 WP_002468344.1 accessory gene regulator AgrB -
  ACLKMS_RS03950 (ACLKMS_03950) hld 845166..845243 (+) 78 WP_002494082.1 delta-hemolysin -
  ACLKMS_RS03955 (ACLKMS_03955) - 845624..846409 (-) 786 WP_049377024.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.97 Da        Isoelectric Point: 5.6250

>NTDB_id=1096264 ACLKMS_RS03930 WP_001829999.1 842093..842809(-) (agrA) [Staphylococcus epidermidis strain BP21]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1096264 ACLKMS_RS03930 WP_001829999.1 842093..842809(-) (agrA) [Staphylococcus epidermidis strain BP21]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAGCTGACTTATTTGACATTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAAGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCAAAAGAAAGTAATGTAGATACGATTGAGTTAAAGCGGGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGGCTCATTGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ACTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0LF82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374

Multiple sequence alignment