Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   HW08_RS03545 Genome accession   NZ_CP008858
Coordinates   725926..726570 (-) Length   214 a.a.
NCBI ID   WP_003085214.1    Uniprot ID   A0A0H2ZLY6
Organism   Pseudomonas aeruginosa strain F63912     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 720926..731570
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW08_RS32035 - 721293..721650 (+) 358 Protein_676 phage tail protein -
  HW08_RS03520 (HW08_21875) - 722684..722968 (+) 285 WP_003117977.1 hypothetical protein -
  HW08_RS03530 (HW08_21870) - 723375..723980 (+) 606 WP_003101640.1 aminodeoxychorismate/anthranilate synthase component II -
  HW08_RS03535 (HW08_21865) trpD 723982..725031 (+) 1050 WP_003085203.1 anthranilate phosphoribosyltransferase -
  HW08_RS03540 (HW08_21860) trpC 725028..725864 (+) 837 WP_016561543.1 indole-3-glycerol phosphate synthase TrpC -
  HW08_RS03545 (HW08_21855) crp 725926..726570 (-) 645 WP_003085214.1 cAMP-activated global transcriptional regulator CRP Regulator
  HW08_RS03550 (HW08_21850) - 726842..727264 (+) 423 WP_003085219.1 OsmC family protein -
  HW08_RS03555 (HW08_21845) speD 727584..728378 (+) 795 WP_003085223.1 adenosylmethionine decarboxylase -
  HW08_RS03560 (HW08_21840) coq7 728433..729080 (-) 648 WP_003085224.1 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase -
  HW08_RS03565 (HW08_21835) - 729180..729518 (-) 339 WP_003085225.1 histidine triad nucleotide-binding protein -
  HW08_RS03570 (HW08_21830) - 729597..731078 (+) 1482 WP_016561544.1 AAA family ATPase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24225.01 Da        Isoelectric Point: 8.0525

>NTDB_id=109189 HW08_RS03545 WP_003085214.1 725926..726570(-) (crp) [Pseudomonas aeruginosa strain F63912]
MVAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEK
EGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPD
AMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVFGTR

Nucleotide


Download         Length: 645 bp        

>NTDB_id=109189 HW08_RS03545 WP_003085214.1 725926..726570(-) (crp) [Pseudomonas aeruginosa strain F63912]
ATGGTAGCTATTACCCACACACCCAAACTCAAACACCTAGACAAGCTGCTCGCACACTGTCACCGCCGCCGCTACACCGC
AAAGAGCACCATCATCTATGCCGGCGATCGCTGCGAAACGCTGTTCTTCATCATCAAGGGTTCGGTCACCATCCTCATCG
AGGACGACGACGGCCGCGAAATGATCATCGGCTACCTCAACAGCGGTGATTTCTTCGGCGAGCTGGGATTGTTCGAAAAG
GAAGGCAGCGAACAGGAACGCAGCGCCTGGGTTCGCGCCAAGGTGGAATGCGAAGTCGCCGAGATCAGCTATGCGAAGTT
CCGCGAACTGTCGCAGCAGGACTCGGAGATCCTCTACACCCTCGGCAGCCAGATGGCCGACCGCCTGCGCAAGACCACCC
GCAAGGTGGGCGACCTGGCCTTCCTCGACGTCACCGGACGCGTCGCCCGCACCTTGCTGGACCTGTGCCAGCAACCGGAC
GCCATGACCCACCCGGACGGCATGCAGATCAAGATCACCCGCCAGGAGATCGGCCGGATCGTCGGCTGCTCGCGGGAAAT
GGTCGGACGCGTGCTGAAGAGCCTGGAGGAGCAGGGCCTGGTGCATGTGAAAGGAAAGACCATGGTGGTCTTCGGCACCC
GCTGA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(22-114)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(146-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZLY6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

67.327

94.393

0.636
  crp Haemophilus influenzae Rd KW20

60.396

94.393

0.57
  crp Acinetobacter baumannii D1279779

54.545

92.523

0.505

Multiple sequence alignment