Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACFCT9_RS05255 Genome accession   NZ_CP178241
Coordinates   1043892..1044521 (-) Length   209 a.a.
NCBI ID   WP_002481662.1    Uniprot ID   -
Organism   Staphylococcus simulans strain PFJB-50N     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1038892..1049521
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFCT9_RS05225 - 1039358..1040596 (-) 1239 WP_412521375.1 aminopeptidase -
  ACFCT9_RS05230 - 1040633..1040839 (-) 207 WP_412521376.1 DUF1128 family protein -
  ACFCT9_RS05235 - 1041064..1041528 (+) 465 WP_412521377.1 low molecular weight protein-tyrosine-phosphatase -
  ACFCT9_RS05240 - 1041536..1041826 (+) 291 WP_412521378.1 YtxH domain-containing protein -
  ACFCT9_RS05245 - 1041955..1043034 (+) 1080 WP_412521379.1 YihY/virulence factor BrkB family protein -
  ACFCT9_RS05250 - 1043242..1043820 (+) 579 WP_412521380.1 beta-class carbonic anhydrase -
  ACFCT9_RS05255 vraR 1043892..1044521 (-) 630 WP_002481662.1 response regulator transcription factor Regulator
  ACFCT9_RS05260 vraS 1044511..1045554 (-) 1044 WP_412521381.1 sensor histidine kinase Regulator
  ACFCT9_RS05265 liaF 1045551..1046252 (-) 702 WP_412521382.1 cell wall-active antibiotics response protein LiaF -
  ACFCT9_RS05270 - 1046268..1046663 (-) 396 WP_412521383.1 hypothetical protein -
  ACFCT9_RS05275 map 1046779..1047543 (-) 765 WP_412521384.1 type I methionyl aminopeptidase -
  ACFCT9_RS05280 - 1047764..1048750 (+) 987 WP_412521385.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23719.32 Da        Isoelectric Point: 4.6245

>NTDB_id=1088619 ACFCT9_RS05255 WP_002481662.1 1043892..1044521(-) (vraR) [Staphylococcus simulans strain PFJB-50N]
MAIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIEKAHELQPDLILMDLLMEDMDGVEATMQIKKDLPQIKVL
MLTSYIEDNEVYRALDAGVDSYILKTTSASDIAEAIRKTYRNEAVFEAEVLVKMRNRMNQRAELYELLTDREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHDLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1088619 ACFCT9_RS05255 WP_002481662.1 1043892..1044521(-) (vraR) [Staphylococcus simulans strain PFJB-50N]
ATGGCGATTAAAGTATTGTTTGTCGACGACCACGAAATGGTTCGTATCGGCATCTCAAGTTATTTATCTACACAACCTGA
TATCGAAGTCGTCGGGGAAGGCAAATCAGGTAAAGAAGCAATTGAAAAAGCGCATGAATTGCAACCTGATTTAATCTTGA
TGGATTTATTAATGGAGGATATGGATGGCGTAGAAGCGACCATGCAAATCAAAAAAGATTTACCTCAGATTAAAGTACTG
ATGCTGACAAGCTATATTGAAGATAATGAAGTGTATCGTGCTTTAGACGCTGGGGTAGATAGTTATATCTTAAAAACAAC
GAGTGCGAGTGATATCGCAGAAGCAATACGTAAAACGTATCGAAATGAAGCGGTGTTTGAAGCGGAAGTACTCGTTAAAA
TGCGTAATCGCATGAATCAACGTGCTGAGTTATATGAATTATTAACGGATAGAGAAATGGAAATTCTATTGCTTATCGCA
AAAGGATATTCTAATCAAGAAATCGCCAGTGCGTCACATATTACGATTAAAACAGTTAAGACGCATGTGAGTAATATTTT
AAGCAAACTTGAAGTTCAAGATAGAACGCAAGCTGTAATTTATGCTTTCCAACATGATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment