Detailed information NTG1088507

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACLKZ2_RS06255
• Genome accession: NZ_CP178225
• Coordinates: 1332208..1333545 (-)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain PA492
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 1327208..1338545

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLKZ2_RS06225 (ACLKZ2_06225)	pilX	1327859..1328446 (-)	588	WP_003094700.1	type 4a pilus minor pilin PilX	-
ACLKZ2_RS06230 (ACLKZ2_06230)	pilW	1328443..1329267 (-)	825	WP_003094698.1	type 4a pilus minor pilin PilW	-
ACLKZ2_RS06235 (ACLKZ2_06235)	pilV	1329264..1329821 (-)	558	WP_003094697.1	type 4a pilus minor pilin PilV	Machinery gene
ACLKZ2_RS06240 (ACLKZ2_06240)	-	1329812..1330318 (-)	507	WP_003094696.1	Tfp pilus assembly protein FimT/FimU	-
ACLKZ2_RS06245 (ACLKZ2_06245)	-	1330424..1330933 (-)	510	WP_015503652.1	Tfp pilus assembly protein FimT/FimU	-
ACLKZ2_RS06250 (ACLKZ2_06250)	thiO	1331068..1332162 (+)	1095	WP_003094695.1	glycine oxidase ThiO	-
ACLKZ2_RS06255 (ACLKZ2_06255)	pilR	1332208..1333545 (-)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACLKZ2_RS06260 (ACLKZ2_06260)	pilS	1333560..1335152 (-)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
ACLKZ2_RS06265 (ACLKZ2_06265)	-	1335142..1335387 (-)	246	WP_014603563.1	PP0621 family protein	-
ACLKZ2_RS06270 (ACLKZ2_06270)	-	1335544..1336569 (-)	1026	WP_003094687.1	outer membrane protein assembly factor BamD	-
ACLKZ2_RS06275 (ACLKZ2_06275)	rluD	1336715..1337677 (+)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACLKZ2_RS06280 (ACLKZ2_06280)	pgeF	1337674..1338402 (+)	729	WP_003094684.1	peptidoglycan editing factor PgeF	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1088507 ACLKZ2_RS06255 WP_003094694.1 1332208..1333545(-) (pilR) [Pseudomonas aeruginosa strain PA492]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1088507 ACLKZ2_RS06255 WP_003094694.1 1332208..1333545(-) (pilR) [Pseudomonas aeruginosa strain PA492]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTAGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384