Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   HQ24_RS17830 Genome accession   NZ_CP008801
Coordinates   3563136..3563768 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli KLY     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3558136..3568768
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HQ24_RS17800 (HQ24_17240) yheS 3558305..3560218 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  HQ24_RS17805 (HQ24_17245) yheT 3560218..3561240 (+) 1023 WP_000057356.1 hydrolase -
  HQ24_RS17810 (HQ24_17250) yheU 3561234..3561452 (+) 219 WP_000907085.1 YheU family protein -
  HQ24_RS17815 (HQ24_17255) prkB 3561506..3562375 (+) 870 WP_001274680.1 phosphoribulokinase -
  HQ24_RS17820 (HQ24_17260) yhfA 3562430..3562834 (-) 405 WP_001148908.1 OsmC family protein -
  HQ24_RS17830 (HQ24_17265) crp 3563136..3563768 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  HQ24_RS17835 (HQ24_17270) yhfK 3563819..3565909 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  HQ24_RS17840 (HQ24_17275) argD 3565976..3567196 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  HQ24_RS17845 (HQ24_17280) pabA 3567282..3567845 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  HQ24_RS17850 (HQ24_17285) fic 3567877..3568479 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  HQ24_RS17855 yhfG 3568469..3568636 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=108752 HQ24_RS17830 WP_000242755.1 3563136..3563768(+) (crp) [Escherichia coli KLY]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=108752 HQ24_RS17830 WP_000242755.1 3563136..3563768(+) (crp) [Escherichia coli KLY]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment