Detailed information NTG1086644

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACLFK2_RS23790
• Genome accession: NZ_CP177307
• Coordinates: 5149352..5150689 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain Pa021
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5144352..5155689

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLFK2_RS23765 (ACLFK2_23765)	pgeF	5144495..5145223 (-)	729	WP_003112833.1	peptidoglycan editing factor PgeF	-
ACLFK2_RS23770 (ACLFK2_23770)	rluD	5145220..5146182 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACLFK2_RS23775 (ACLFK2_23775)	-	5146328..5147353 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACLFK2_RS23780 (ACLFK2_23780)	-	5147510..5147755 (+)	246	WP_003102591.1	PP0621 family protein	-
ACLFK2_RS23785 (ACLFK2_23785)	pilS	5147745..5149337 (+)	1593	WP_034029881.1	two-component system sensor histidine kinase PilS	Regulator
ACLFK2_RS23790 (ACLFK2_23790)	pilR	5149352..5150689 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACLFK2_RS23795 (ACLFK2_23795)	thiO	5150735..5151829 (-)	1095	WP_034029886.1	glycine oxidase ThiO	-
ACLFK2_RS23800 (ACLFK2_23800)	-	5151964..5152473 (+)	510	WP_003102595.1	Tfp pilus assembly protein FimT/FimU	-
ACLFK2_RS23805 (ACLFK2_23805)	-	5152579..5153085 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ACLFK2_RS23810 (ACLFK2_23810)	pilV	5153076..5153633 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ACLFK2_RS23815 (ACLFK2_23815)	pilW	5153630..5154454 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ACLFK2_RS23820 (ACLFK2_23820)	pilX	5154451..5155038 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1086644 ACLFK2_RS23790 WP_003094694.1 5149352..5150689(+) (pilR) [Pseudomonas aeruginosa strain Pa021]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1086644 ACLFK2_RS23790 WP_003094694.1 5149352..5150689(+) (pilR) [Pseudomonas aeruginosa strain Pa021]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTAGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGATACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384