Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   ACJWMC_RS04875 Genome accession   NZ_CP177181
Coordinates   966677..968017 (+) Length   446 a.a.
NCBI ID   WP_002890839.1    Uniprot ID   J7SIL7
Organism   Streptococcus salivarius strain MRD1919     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 961677..973017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS04845 - 962432..963082 (-) 651 WP_002890834.1 amino acid ABC transporter permease -
  ACJWMC_RS04850 - 963094..963792 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  ACJWMC_RS04855 - 963810..964643 (-) 834 WP_037597730.1 transporter substrate-binding domain-containing protein -
  ACJWMC_RS04860 - 964655..965422 (-) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  ACJWMC_RS04865 - 965609..965809 (-) 201 Protein_913 amino acid ABC transporter permease -
  ACJWMC_RS04870 vicR 965977..966684 (+) 708 WP_002890837.1 response regulator YycF Regulator
  ACJWMC_RS04875 vicK 966677..968017 (+) 1341 WP_002890839.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACJWMC_RS04880 vicX 968023..968835 (+) 813 WP_037598119.1 MBL fold metallo-hydrolase Regulator
  ACJWMC_RS04885 - 968895..969254 (+) 360 WP_037597735.1 YbaN family protein -
  ACJWMC_RS04890 - 969306..970520 (-) 1215 WP_002890844.1 aminoacyltransferase -
  ACJWMC_RS04895 yidA 970522..971331 (-) 810 WP_002890845.1 sugar-phosphatase -
  ACJWMC_RS04900 - 971510..972367 (+) 858 WP_002890846.1 GNAT family N-acetyltransferase -
  ACJWMC_RS04905 - 972459..972845 (+) 387 WP_002890847.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50976.18 Da        Isoelectric Point: 5.0702

>NTDB_id=1085941 ACJWMC_RS04875 WP_002890839.1 966677..968017(+) (vicK) [Streptococcus salivarius strain MRD1919]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDSELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETATQMSILDLLDGENPYTYNELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFVSGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTDKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1085941 ACJWMC_RS04875 WP_002890839.1 966677..968017(+) (vicK) [Streptococcus salivarius strain MRD1919]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTTTTTGTGGCTTTCTACTTTAT
TTTTCTTGCTTATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGAGTCAAGTCCCTAATGGCAGGTA
ACTATAATGAGGAGTTACGCTTAAAGGGTGATTCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGACGTT
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTATATGAGTGATGGAGTCAT
TGCGACTAATCGACGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAATGAATTGTTATCTAAGACTCCTGAGATT
CATTTGTCTCGTCGAGATGCCAACGATGAGTTTGTGACCCTACGCGTTAACTTTGCCCTTATTCGTAAAGAATCTGGTTT
TGTCTCAGGTCTGGTTGCCGTCCTTCACGATGCCACTGAGCAGGAAAAAGAAGAGCGGGAACGCCGACTCTTTGTATCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCTTATCTGGAGGCACTTGATGATGGTGCTCTTGACGAA
GAGATTGCCCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
GTCTCGTATTGACAATAAGAGTACCCAGCTTGACGTTGAAATGACTAATTTCACGGCCTTCATGACCTATATATTGAATC
GTTTCGATCAGATTAAGAGTCAAGAAACCAATACAGATAAAACTTACGAAATTATTCGAGATTATCCGGTAAACTCGATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATCCTTAATAATGCTATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGTATTCCTA
AGAAGGATTTGCCGTTAATTTTTGACCGTTTTTACCGTGTTGATAAGGCTAGAAGTCGTGCTCAGGGTGGAACTGGTCTT
GGCTTGTCCATTGCAAAAGAAATTGTTAAGCAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(38-79)

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIL7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.155

92.825

0.688
  micB Streptococcus pneumoniae Cp1015

67.436

97.085

0.655

Multiple sequence alignment