Detailed information NTG1085887

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: ACJVG6_RS07895
• Genome accession: NZ_CP177180
• Coordinates: 1684031..1684726 (-)
• Length: 231 a.a.
• NCBI ID: WP_004183181.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain MRD-KRBY
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
ICE	1671365..1688070	1684031..1684726	within	0

Gene organization within MGE regions

Location: 1671365..1688070

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJVG6_RS07850	-	1673389..1674156 (+)	768	WP_004183166.1	replication-relaxation family protein	-
ACJVG6_RS07855	-	1674332..1675999 (+)	1668	WP_004183168.1	recombinase family protein	-
ACJVG6_RS07860	-	1676108..1676617 (-)	510	WP_004183169.1	QueT transporter family protein	-
ACJVG6_RS07865	-	1676708..1677667 (-)	960	WP_004183170.1	YihY/virulence factor BrkB family protein	-
ACJVG6_RS07870	-	1677669..1678529 (-)	861	WP_004183173.1	methionyl aminopeptidase	-
ACJVG6_RS07875	spxR	1678569..1679849 (-)	1281	WP_004183175.1	CBS-HotDog domain-containing transcription factor SpxR	-
ACJVG6_RS07880	-	1679842..1680387 (-)	546	WP_004183177.1	GNAT family N-acetyltransferase	-
ACJVG6_RS07885	-	1680453..1681715 (-)	1263	WP_004183178.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ACJVG6_RS07890	-	1681801..1684041 (-)	2241	WP_004183180.1	DNA internalization-related competence protein ComEC/Rec2	-
ACJVG6_RS07895	comEA	1684031..1684726 (-)	696	WP_004183181.1	helix-hairpin-helix domain-containing protein	Machinery gene
ACJVG6_RS07900	-	1684835..1685590 (-)	756	WP_004183182.1	lysophospholipid acyltransferase family protein	-
ACJVG6_RS07905	-	1685720..1686655 (+)	936	WP_037605714.1	polysaccharide deacetylase family protein	-
ACJVG6_RS07910	-	1686705..1687469 (+)	765	WP_004183185.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
ACJVG6_RS07915	-	1687473..1687742 (+)	270	WP_004183187.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 231 a.a.
• Molecular weight: 24284.10 Da
• Isoelectric Point: 4.5517

>NTDB_id=1085887 ACJVG6_RS07895 WP_004183181.1 1684031..1684726(-) (comEA) [Streptococcus salivarius strain MRD-KRBY]
MKEKILAYVKDNCLFVSVIAVLMVIFCFFLWMTYGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKGE
SKVTVDVKGAVANPGVYTLKASARVTDAIKAAGGMTEDADAKSVNLAASLSDEEVVYVATKDENLSVLGQSGTGQVSDKG
GQTSAKDGKINLNTATSEELQTISGIGAKRAEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide

• Length: 696 bp

>NTDB_id=1085887 ACJVG6_RS07895 WP_004183181.1 1684031..1684726(-) (comEA) [Streptococcus salivarius strain MRD-KRBY]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATTGTCTGTTTGTGAGTGTTATTGCTGTACTGATGGTGATTTTTTG
CTTCTTCCTATGGATGACTTACGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CCTCCTCCTCCAAACAAAGCTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACTGAAGGAAGTGAAAAGGGTGAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGCTAATCCGGGTGTTTATACCTTAAAAGCAAGCGCTAGGGTGACTGA
TGCCATCAAAGCCGCTGGGGGAATGACTGAGGATGCGGATGCTAAGAGTGTTAACTTAGCTGCAAGCTTGTCAGACGAAG
AGGTTGTCTATGTGGCAACTAAGGATGAAAACCTCTCTGTTCTTGGTCAATCAGGAACTGGTCAGGTCTCTGACAAAGGA
GGGCAAACTAGTGCTAAGGATGGCAAAATCAACTTAAACACAGCGACTTCAGAGGAGTTGCAAACCATTTCTGGGATTGG
AGCTAAGCGTGCTGAGGATATCATTGCCTATCGTGAAAGTCATGGTGGCTTTCAATCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACTTTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (85-138)

• Helix-hairpin-helix motif (HHH_3) (168-228)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Streptococcus thermophilus LMD-9	91.775	100	0.918
comEA/celA/cilE	Streptococcus mitis SK321	41.048	99.134	0.407
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	40.611	99.134	0.403