Detailed information    

insolico Bioinformatically predicted

Overview

Name   CJE1441   Type   Regulator
Locus tag   CLC19245_RS04250 Genome accession   NZ_CP176606
Coordinates   800952..801608 (+) Length   218 a.a.
NCBI ID   WP_257395552.1    Uniprot ID   -
Organism   Campylobacter lari subsp. concheus strain RM19245     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 789667..847253 800952..801608 within 0


Gene organization within MGE regions


Location: 789667..847253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CLC19245_RS04180 - 789667..791127 (-) 1461 Protein_798 DNA translocase FtsK -
  CLC19245_RS04185 (CLC19245_00831) flgL 792550..794787 (-) 2238 WP_257395556.1 flagellar hook-associated protein FlgL -
  CLC19245_RS04195 (CLC19245_00833) - 795221..796399 (+) 1179 WP_257395555.1 tyrosine-type recombinase/integrase -
  CLC19245_RS04200 (CLC19245_00834) - 796392..796577 (-) 186 WP_012661534.1 helix-turn-helix transcriptional regulator -
  CLC19245_RS04205 (CLC19245_00835) - 796579..796935 (-) 357 WP_012661535.1 hypothetical protein -
  CLC19245_RS04210 (CLC19245_00836) - 796951..797157 (-) 207 WP_214126389.1 hypothetical protein -
  CLC19245_RS04215 (CLC19245_00837) - 797141..797515 (-) 375 WP_087699185.1 hypothetical protein -
  CLC19245_RS04220 (CLC19245_00838) - 797512..798378 (-) 867 WP_257395554.1 hypothetical protein -
  CLC19245_RS04225 (CLC19245_00839) - 798399..798557 (-) 159 WP_012661539.1 hypothetical protein -
  CLC19245_RS04230 (CLC19245_00840) - 798560..798739 (-) 180 WP_214098770.1 hypothetical protein -
  CLC19245_RS04235 (CLC19245_00841) - 799088..799387 (-) 300 WP_012661541.1 hypothetical protein -
  CLC19245_RS04240 (CLC19245_00842) - 799388..799594 (-) 207 WP_041570280.1 hypothetical protein -
  CLC19245_RS04245 (CLC19245_00843) - 799817..800950 (+) 1134 WP_257395553.1 helix-turn-helix domain-containing protein -
  CLC19245_RS04250 (CLC19245_00844) CJE1441 800952..801608 (+) 657 WP_257395552.1 DNA/RNA non-specific endonuclease Regulator
  CLC19245_RS04255 (CLC19245_00845) - 801819..803747 (+) 1929 WP_257395551.1 KAP family NTPase -
  CLC19245_RS04260 (CLC19245_00846) - 803728..803880 (-) 153 WP_235362394.1 hypothetical protein -
  CLC19245_RS04265 (CLC19245_00847) - 803864..804253 (-) 390 WP_410708194.1 hypothetical protein -
  CLC19245_RS04270 (CLC19245_00848) - 804483..804950 (-) 468 WP_257395676.1 DUF5675 family protein -
  CLC19245_RS04275 (CLC19245_00849) - 804951..806393 (-) 1443 WP_257395675.1 collagen-like protein -
  CLC19245_RS04280 (CLC19245_00850) - 806394..806765 (-) 372 WP_257395674.1 DUF1353 domain-containing protein -
  CLC19245_RS04285 (CLC19245_00851) - 806746..807243 (-) 498 WP_047208161.1 hypothetical protein -
  CLC19245_RS04290 (CLC19245_00852) - 807245..808990 (-) 1746 WP_257395673.1 radical SAM/SPASM domain-containing protein -
  CLC19245_RS04295 (CLC19245_00853) - 808990..809625 (-) 636 WP_257395672.1 hypothetical protein -
  CLC19245_RS04300 (CLC19245_00854) - 809636..810841 (-) 1206 WP_257395671.1 hypothetical protein -
  CLC19245_RS04305 (CLC19245_00855) - 810841..811452 (-) 612 WP_012661557.1 hypothetical protein -
  CLC19245_RS04310 (CLC19245_00856) - 811439..811765 (-) 327 WP_066006885.1 head-tail adaptor protein -
  CLC19245_RS04315 (CLC19245_00857) - 811775..812212 (-) 438 WP_012661559.1 head-tail connector protein -
  CLC19245_RS04320 - 812209..812529 (-) 321 WP_410708195.1 hypothetical protein -
  CLC19245_RS04325 (CLC19245_00858) - 812540..813697 (-) 1158 WP_257395610.1 phage major capsid protein -
  CLC19245_RS04330 (CLC19245_00859) - 813708..814259 (-) 552 WP_066006888.1 HK97 family phage prohead protease -
  CLC19245_RS04335 (CLC19245_00860) - 814341..815210 (-) 870 WP_066006890.1 hypothetical protein -
  CLC19245_RS04340 - 815207..817843 (-) 2637 WP_257395611.1 hypothetical protein -
  CLC19245_RS04345 - 817837..820434 (-) 2598 WP_257395612.1 hypothetical protein -
  CLC19245_RS04350 (CLC19245_00862) - 820491..820814 (+) 324 WP_257395613.1 hypothetical protein -
  CLC19245_RS04355 (CLC19245_00863) - 820806..821024 (-) 219 WP_214126405.1 hypothetical protein -
  CLC19245_RS04360 (CLC19245_00864) - 821105..821476 (-) 372 WP_214098817.1 DNA repair protein -
  CLC19245_RS04365 (CLC19245_00865) - 821473..822447 (-) 975 WP_257395614.1 hypothetical protein -
  CLC19245_RS04370 (CLC19245_00866) - 822511..822861 (-) 351 WP_214126407.1 hypothetical protein -
  CLC19245_RS04375 (CLC19245_00867) - 822861..823385 (-) 525 WP_094750273.1 HK97 gp10 family phage protein -
  CLC19245_RS04380 (CLC19245_00868) - 823373..824542 (-) 1170 WP_257395615.1 phage portal protein -
  CLC19245_RS04385 (CLC19245_00869) - 824661..826364 (+) 1704 WP_257395616.1 KAP family NTPase -
  CLC19245_RS04390 (CLC19245_00870) - 826449..827078 (+) 630 WP_257395617.1 helix-turn-helix transcriptional regulator -
  CLC19245_RS04395 (CLC19245_00871) - 827136..827456 (+) 321 WP_257395618.1 hypothetical protein -
  CLC19245_RS04400 (CLC19245_00872) - 827473..827667 (+) 195 WP_318529555.1 hypothetical protein -
  CLC19245_RS04405 (CLC19245_00873) - 827735..828022 (+) 288 WP_257395620.1 ankyrin repeat domain-containing protein -
  CLC19245_RS04410 (CLC19245_00874) - 828059..828871 (-) 813 WP_257395621.1 DNA adenine methylase -
  CLC19245_RS04415 (CLC19245_00875) - 828976..830607 (-) 1632 WP_012661576.1 terminase large subunit -
  CLC19245_RS04420 (CLC19245_00876) - 830600..831235 (-) 636 WP_257395622.1 P27 family phage terminase small subunit -
  CLC19245_RS04425 (CLC19245_00877) - 831399..831830 (-) 432 WP_257395623.1 HNH endonuclease -
  CLC19245_RS04430 (CLC19245_00878) - 831827..832105 (-) 279 WP_257395624.1 hypothetical protein -
  CLC19245_RS04435 - 832974..833132 (-) 159 WP_257395625.1 hypothetical protein -
  CLC19245_RS04440 - 833208..833372 (-) 165 WP_257395182.1 hypothetical protein -
  CLC19245_RS04445 (CLC19245_00880) - 833825..834049 (-) 225 WP_257395626.1 hypothetical protein -
  CLC19245_RS04450 (CLC19245_00881) - 834204..834591 (-) 388 Protein_851 hypothetical protein -
  CLC19245_RS04455 (CLC19245_00882) - 835121..836041 (+) 921 WP_257395312.1 helix-turn-helix transcriptional regulator -
  CLC19245_RS04460 (CLC19245_00883) - 836046..837464 (-) 1419 WP_257395311.1 PD-(D/E)XK nuclease family protein -
  CLC19245_RS04465 (CLC19245_00884) - 837572..838045 (+) 474 WP_220524506.1 hypothetical protein -
  CLC19245_RS04470 (CLC19245_00885) - 838174..838971 (+) 798 WP_257395186.1 DNA-methyltransferase -
  CLC19245_RS04475 (CLC19245_00886) - 838966..839736 (-) 771 WP_257395187.1 hypothetical protein -
  CLC19245_RS04480 (CLC19245_00887) - 839906..841828 (+) 1923 WP_257395310.1 AAA family ATPase -
  CLC19245_RS04485 (CLC19245_00888) - 842074..843240 (+) 1167 Protein_858 DUF262 domain-containing protein -
  CLC19245_RS04490 - 843259..843630 (+) 372 WP_257395314.1 HNH endonuclease family protein -
  CLC19245_RS04495 (CLC19245_00889) dnaE 843660..847253 (-) 3594 WP_257395189.1 DNA polymerase III subunit alpha -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25768.53 Da        Isoelectric Point: 10.0413

>NTDB_id=1081508 CLC19245_RS04250 WP_257395552.1 800952..801608(+) (CJE1441) [Campylobacter lari subsp. concheus strain RM19245]
MLKKIFLLALFTSLSFAKYTQYKPSEDFAKYFTTQNCSQVLDKFYYINCYDYNYKGTKAVAYKLEADNLKGEQIKKRPRF
EDDTNIPKKYRTTWSDYKNSGYDRGHTLSNASMRKTTQAQRSTFLMSNITPQNPQVNQKVWNKIEKRERQIALKLGEIEV
LNLVNYDSNPQRIKNQIAIPNSYIKIIKGNNFKECYKVPNYKVESENVKLYKIQCNFL

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1081508 CLC19245_RS04250 WP_257395552.1 800952..801608(+) (CJE1441) [Campylobacter lari subsp. concheus strain RM19245]
ATGCTTAAAAAGATATTTTTATTAGCGCTATTTACCTCATTGTCTTTTGCAAAGTACACACAATATAAACCGAGTGAAGA
TTTTGCAAAGTATTTTACTACACAAAATTGCTCTCAAGTTTTAGATAAATTTTATTATATTAATTGTTATGATTATAACT
ACAAAGGTACTAAAGCAGTAGCTTATAAATTAGAAGCAGATAATCTAAAAGGCGAACAAATCAAAAAGCGTCCGCGCTTT
GAAGATGATACAAATATCCCTAAAAAATATCGCACCACTTGGAGTGATTATAAAAATAGTGGTTATGATAGAGGACATAC
CCTTTCTAATGCCTCTATGAGAAAAACTACTCAAGCTCAAAGAAGTACATTCTTAATGAGTAATATTACTCCGCAAAATC
CACAAGTTAATCAAAAAGTATGGAATAAGATTGAAAAAAGAGAAAGGCAAATAGCTTTAAAGCTTGGAGAAATTGAAGTT
TTAAATTTAGTTAATTATGATAGCAACCCTCAAAGAATAAAAAATCAAATTGCTATTCCAAACTCTTATATCAAAATTAT
AAAAGGTAATAATTTTAAAGAATGCTATAAAGTTCCAAATTATAAAGTGGAAAGTGAGAATGTAAAACTATATAAAATAC
AATGTAACTTTCTTTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(26-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  CJE1441 Campylobacter jejuni RM1221

83.721

98.624

0.826
  CJE0566 Campylobacter jejuni RM1221

83.721

98.624

0.826

Multiple sequence alignment