Detailed information    

experimental Experimentally validated

Overview

Name   CJE1441   Type   Regulator
Locus tag   CJE_RS07175 Genome accession   NC_003912
Coordinates   1346482..1347135 (+) Length   217 a.a.
NCBI ID   WP_011049930.1    Uniprot ID   -
Organism   Campylobacter jejuni RM1221     
Function   repress natural transformation   
Competence regulation

Function

Genetic transfer of the genes to a naturally transformable C. jejuni strain resulted in a decreased efficiency of natural transformation.


Genomic Context

Location: 1341482..1352135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CJE_RS07135 - 1342219..1342449 (-) 231 WP_002787283.1 hypothetical protein -
  CJE_RS07140 (CJE1433) - 1342415..1342678 (-) 264 WP_002787281.1 hypothetical protein -
  CJE_RS07145 (CJE1434) - 1342735..1343022 (-) 288 WP_002787279.1 YopX family protein -
  CJE_RS07150 (CJE1435) - 1343075..1343806 (-) 732 WP_011049928.1 phage regulatory protein/antirepressor Ant -
  CJE_RS07155 (CJE1436) - 1344237..1344521 (-) 285 WP_002912332.1 hypothetical protein -
  CJE_RS07160 (CJE1438) - 1344518..1344721 (-) 204 WP_002870299.1 hypothetical protein -
  CJE_RS07165 (CJE1439) - 1344926..1345579 (+) 654 WP_002870336.1 hypothetical protein -
  CJE_RS07170 (CJE1440) - 1345814..1346476 (+) 663 WP_002870274.1 S24 family peptidase -
  CJE_RS07175 (CJE1441) CJE1441 1346482..1347135 (+) 654 WP_011049930.1 DNA/RNA non-specific endonuclease Regulator
  CJE_RS07180 (CJE1442) - 1347152..1347433 (+) 282 WP_002870263.1 PLDc N-terminal domain-containing protein -
  CJE_RS09755 (CJE1443) - 1347447..1347644 (-) 198 WP_002913413.1 hypothetical protein -
  CJE_RS07185 (CJE1444) - 1347562..1347981 (-) 420 WP_002870261.1 hypothetical protein -
  CJE_RS07190 (CJE1445) - 1348210..1348671 (-) 462 WP_002870260.1 DUF5675 family protein -
  CJE_RS07195 (CJE1447) - 1348720..1350003 (-) 1284 WP_011049931.1 hypothetical protein -
  CJE_RS07200 (CJE1448) - 1350000..1350374 (-) 375 WP_011049932.1 DUF1353 domain-containing protein -
  CJE_RS07205 (CJE1449) - 1350367..1350750 (-) 384 WP_002869963.1 hypothetical protein -
  CJE_RS07210 (CJE1450) - 1350747..1351382 (-) 636 WP_002789149.1 DUF4376 domain-containing protein -
  CJE_RS07215 (CJE1451) - 1351395..1351844 (-) 450 WP_002798141.1 hypothetical protein -

Sequence

Protein


Download         Length: 217 a.a.        Molecular weight: 25531.02 Da        Isoelectric Point: 9.8742

>NTDB_id=1225 CJE_RS07175 WP_011049930.1 1346482..1347135(+) (CJE1441) [Campylobacter jejuni RM1221]
MKKLIILSLLSTLAFADYTQYKPSEDFAKYFTKQNCSQVLDKFYYINCYDYSLKGTKAVAYRLEADNLKGEQIKKRPRFE
DDTNIPKKYRTTWSDYKNSGYDRGHTLSNASMRKTTQAQRSTFLMSNITPQNPQINQRVWNKIEKRERQVALKLGSLEVL
NLVNYDNNPQRIKNNIAIPSSYTKILKGDNFKECYQVPNHDVENENLRIYKVKCDNF

Nucleotide


Download         Length: 654 bp        

>NTDB_id=1225 CJE_RS07175 WP_011049930.1 1346482..1347135(+) (CJE1441) [Campylobacter jejuni RM1221]
ATGAAAAAACTTATAATCTTATCTTTATTATCCACTCTAGCTTTTGCTGATTATACACAATACAAACCAAGCGAAGATTT
TGCCAAGTATTTTACTAAACAAAACTGCTCACAAGTTTTGGATAAATTTTATTATATTAATTGTTATGATTATTCTTTAA
AAGGCACTAAAGCCGTAGCTTATAGATTAGAAGCGGATAATTTAAAAGGCGAACAAATCAAAAAACGCCCACGCTTTGAA
GATGATACAAATATTCCTAAAAAATACCGCACCACATGGAGTGATTATAAAAACAGCGGTTACGACAGGGGACACACTCT
TTCTAATGCTTCAATGAGAAAAACAACTCAAGCTCAAAGAAGCACTTTTTTAATGAGCAACATTACTCCACAAAATCCAC
AAATCAATCAAAGAGTTTGGAATAAAATTGAAAAAAGAGAAAGACAAGTAGCTTTAAAGCTTGGAAGTTTAGAAGTTTTA
AATTTGGTTAATTATGACAATAATCCACAAAGAATAAAAAACAATATTGCTATTCCAAGCTCTTACACTAAGATTTTAAA
AGGTGATAATTTTAAAGAATGTTACCAAGTGCCTAATCACGATGTAGAAAATGAGAATTTAAGAATATATAAAGTAAAAT
GTGACAATTTTTAA

Domains

Predicted by InterProScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(27-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  CJE0566 Campylobacter jejuni RM1221

91.163

99.078

0.903

Multiple sequence alignment    



References

[1] Esther J Gaasbeek et al. (2010) Nucleases encoded by the integrated elements CJIE2 and CJIE4 inhibit natural transformation of Campylobacter jejuni. Journal of Bacteriology 192(4):936-41. [PMID: 20023031]