Detailed information NTG1080695

Bioinformatically predicted

Overview

• Name: comP
• Type: Regulator
• Locus tag: ACKW6F_RS14880
• Genome accession: NZ_CP176527
• Coordinates: 2898924..2901215 (-)
• Length: 763 a.a.
• NCBI ID: WP_024425943.1
• Uniprot ID: A0A5C0WIX2
• Organism: Bacillus safensis strain D-62
• Function: phosphorylation of ComA (predicted from homology) Competence regulation

Genomic Context

Location: 2893924..2906215

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACKW6F_RS14840 (ACKW6F_14840)	-	2894330..2894761 (+)	432	WP_024423315.1	Na(+)/H(+) antiporter subunit B	-
ACKW6F_RS14845 (ACKW6F_14845)	-	2894761..2895102 (+)	342	WP_024423316.1	Na(+)/H(+) antiporter subunit C	-
ACKW6F_RS14850 (ACKW6F_14850)	-	2895095..2896573 (+)	1479	WP_024425940.1	Na+/H+ antiporter subunit D	-
ACKW6F_RS14855 (ACKW6F_14855)	-	2896580..2897059 (+)	480	WP_024425941.1	Na+/H+ antiporter subunit E	-
ACKW6F_RS14860 (ACKW6F_14860)	-	2897059..2897340 (+)	282	WP_024425942.1	Na(+)/H(+) antiporter subunit F1	-
ACKW6F_RS14865 (ACKW6F_14865)	mnhG	2897324..2897698 (+)	375	WP_024423320.1	monovalent cation/H(+) antiporter subunit G	-
ACKW6F_RS14870 (ACKW6F_14870)	-	2897789..2898178 (-)	390	WP_024423321.1	hotdog fold thioesterase	-
ACKW6F_RS14875 (ACKW6F_14875)	comA	2898202..2898843 (-)	642	WP_024423322.1	response regulator transcription factor	Regulator
ACKW6F_RS14880 (ACKW6F_14880)	comP	2898924..2901215 (-)	2292	WP_024425943.1	ATP-binding protein	Regulator
ACKW6F_RS14885 (ACKW6F_14885)	comX	2901229..2901402 (-)	174	WP_024425944.1	competence pheromone ComX	-
ACKW6F_RS14890 (ACKW6F_14890)	-	2901380..2902303 (-)	924	WP_024425945.1	polyprenyl synthetase family protein	-
ACKW6F_RS14895 (ACKW6F_14895)	degQ	2902455..2902595 (-)	141	WP_003213123.1	degradation enzyme regulation protein DegQ	Regulator
ACKW6F_RS14900 (ACKW6F_14900)	-	2903101..2903457 (+)	357	WP_024425946.1	hypothetical protein	-
ACKW6F_RS14905 (ACKW6F_14905)	-	2903493..2904719 (-)	1227	WP_024425947.1	EAL and HDOD domain-containing protein	-

Sequence

Protein

• Length: 763 a.a.
• Molecular weight: 88009.32 Da
• Isoelectric Point: 7.0526

>NTDB_id=1080695 ACKW6F_RS14880 WP_024425943.1 2898924..2901215(-) (comP) [Bacillus safensis strain D-62]
MQKFYSKLTVILMILSFIYVIYISYINVFNIFVGAVVSVNSDGQLEIEDVVDFTDSYYAGVRKGDIILEVNGNKEPTEEV
RRGYLANVKSLVVDRHGDEIEIENVSLLSQENLFIYIIPIIFYSICLFCIFMILKINKSRKKESAYILALFLLAVAVAYV
SSGGSGKGEYISSFVVIFTMTSVPSLYMHFMYQYLKELGTVIISWRVLLCLYAVPFINIVLEILFKNMVLAAFNLLSFFA
LAFITIIITLRAAKKLKGTEIGNVLSAFALILISSFSPFMLFFIIPYLFHKYFISPYILASFALLIPFFLVYQFMTNKLY
NVDFFLGRIKYYSLLAITPTIAVVVIFDFIQKPSANFYTMKFTIITYILMLTVFYFKEIIDFRFRLKRFSEKHNYQDSVF
KFTQLIREASSLHQVFYHLKYTILEVLVVNKAFVLEVKADGQVEEIDESTEDSKLWKKYVDQFQELLGEVGKIIALDKGF
MMKIGERGGHSFVICCLSNLRTPKLSRDEISWLKTLAFYTSVSLENVVKIEELMEHLDDLKQREANPAWLKKIMFAMEEK
QRSDLARDLHDSVLQDLISLKRQSEMFLTNFQNNQCPTSIENSLISWNDQMSKVIQTTRETCHELRPQLLYDLGLVKAIS
KLTSQIQEEAPFHIRLNTTRFDKELDIDIDSQLNIYRIVQELLSNALKHSKATQVLVMLICIKDQVVLHYEDDGVGFDAS
HLDQHTMSMGLSGIRERVKALNGKLQIHTAPEKGLKVKIEMEL

Nucleotide

• Length: 2292 bp

>NTDB_id=1080695 ACKW6F_RS14880 WP_024425943.1 2898924..2901215(-) (comP) [Bacillus safensis strain D-62]
ATGCAAAAATTTTACTCGAAATTAACTGTTATATTAATGATCCTTAGCTTTATTTATGTGATTTATATTTCCTACATCAA
TGTGTTTAATATTTTTGTAGGAGCAGTCGTTTCGGTGAATAGTGACGGCCAACTTGAAATAGAGGATGTTGTTGATTTTA
CAGACAGCTATTATGCTGGTGTTAGGAAAGGCGATATCATCCTTGAAGTGAACGGTAACAAAGAACCAACCGAAGAAGTA
AGACGAGGTTATTTAGCGAATGTCAAGAGTTTAGTTGTTGATAGACATGGTGATGAAATTGAAATAGAGAATGTAAGCTT
ATTAAGTCAAGAAAATCTGTTTATTTATATAATACCTATCATTTTTTATTCGATCTGTCTATTCTGTATATTTATGATTT
TAAAAATCAATAAATCTAGGAAAAAAGAGTCTGCATATATTCTAGCTCTCTTTTTGCTAGCTGTTGCTGTAGCCTATGTA
AGCTCTGGCGGCTCTGGTAAAGGGGAATATATTAGCAGCTTTGTCGTAATTTTTACGATGACTAGTGTACCGTCGTTATA
TATGCACTTTATGTATCAATATTTAAAGGAATTAGGAACGGTAATTATTAGTTGGCGTGTACTTCTTTGTTTGTATGCCG
TCCCTTTTATAAATATTGTATTAGAAATTCTGTTTAAAAATATGGTTTTAGCTGCTTTTAACTTACTTTCATTCTTTGCA
CTTGCATTTATTACGATTATTATCACATTAAGGGCTGCTAAAAAGTTGAAAGGGACTGAAATCGGAAATGTCCTTAGTGC
CTTTGCACTTATCTTGATCTCATCATTCAGTCCATTTATGCTATTTTTTATTATTCCTTATTTATTTCATAAATATTTTA
TTTCACCTTATATCCTAGCATCGTTCGCTTTATTGATTCCGTTTTTCTTAGTCTATCAATTTATGACAAATAAATTATAT
AATGTTGATTTCTTTTTGGGGAGAATCAAATATTATAGTCTTTTAGCCATCACACCTACTATAGCGGTAGTCGTTATATT
TGATTTCATTCAGAAGCCAAGTGCTAACTTTTATACAATGAAATTTACGATTATCACGTATATTCTTATGCTCACTGTCT
TCTATTTTAAAGAAATCATCGACTTCCGTTTTCGATTGAAGCGTTTTTCAGAGAAGCATAATTATCAAGATAGCGTGTTT
AAATTCACGCAGCTCATTCGTGAGGCGTCATCACTTCACCAAGTGTTCTATCATTTAAAATACACCATTTTAGAAGTACT
TGTTGTGAACAAAGCCTTTGTGCTTGAAGTGAAGGCAGATGGACAGGTTGAAGAGATTGATGAATCTACAGAGGACAGTA
AGCTATGGAAAAAGTATGTAGACCAATTTCAGGAATTATTAGGTGAAGTTGGAAAAATTATTGCGCTTGATAAAGGATTC
ATGATGAAAATTGGTGAGCGGGGCGGTCACTCTTTTGTGATTTGTTGTTTATCTAATTTACGGACACCGAAATTGTCGCG
TGATGAGATTTCTTGGTTGAAAACATTGGCCTTTTATACAAGTGTCAGTTTAGAAAATGTTGTCAAAATCGAAGAGTTGA
TGGAGCATCTTGACGATTTGAAACAGCGTGAGGCCAATCCTGCCTGGCTGAAGAAAATCATGTTTGCTATGGAAGAGAAG
CAGCGTTCAGATTTAGCGAGAGATCTTCATGATTCCGTGCTGCAGGACTTGATATCACTAAAAAGGCAGTCGGAGATGTT
TTTAACGAATTTCCAAAACAACCAATGCCCTACATCTATTGAAAATTCGCTTATCTCATGGAATGATCAAATGTCCAAAG
TGATTCAAACGACGAGAGAAACGTGTCATGAGCTTCGCCCGCAGCTGCTGTATGATTTAGGTTTAGTAAAGGCGATATCG
AAGCTGACTTCTCAAATTCAGGAGGAAGCGCCGTTTCATATTAGGCTGAATACGACACGCTTTGATAAAGAATTGGACAT
TGATATTGATTCACAGCTGAATATTTACCGAATTGTTCAGGAGCTGTTATCCAATGCCCTGAAGCATTCGAAAGCCACTC
AAGTGTTAGTGATGCTGATTTGTATTAAAGATCAGGTTGTTCTTCACTATGAGGATGATGGAGTCGGTTTTGATGCCAGT
CATCTTGATCAGCACACAATGAGCATGGGGCTATCGGGAATTAGAGAACGAGTGAAAGCGTTAAATGGAAAGCTTCAAAT
TCACACAGCCCCGGAAAAAGGGCTTAAGGTGAAAATTGAAATGGAATTGTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (562-630)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (674-761)

3D structure

• AlphaFold DB: A0A5C0WIX2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Bacillus subtilis subsp. subtilis str. 168	49.229	100	0.502