Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ACKN8U_RS02685 Genome accession   NZ_CP176035
Coordinates   577717..578349 (+) Length   210 a.a.
NCBI ID   WP_005381432.1    Uniprot ID   U2ZZI4
Organism   Vibrio parahaemolyticus strain L2181     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 572717..583349
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKN8U_RS02660 (ACKN8U_02660) - 572737..574656 (+) 1920 WP_043043454.1 ABC transporter ATP-binding protein -
  ACKN8U_RS02665 (ACKN8U_02665) - 574653..575141 (+) 489 WP_005458139.1 TIGR02444 family protein -
  ACKN8U_RS02670 (ACKN8U_02670) - 575228..576235 (+) 1008 WP_193282485.1 hydrolase -
  ACKN8U_RS02675 (ACKN8U_02675) - 576269..576481 (+) 213 WP_005458136.1 YheU family protein -
  ACKN8U_RS02680 (ACKN8U_02680) - 576607..577476 (+) 870 WP_005458134.1 phosphoribulokinase -
  ACKN8U_RS02685 (ACKN8U_02685) crp 577717..578349 (+) 633 WP_005381432.1 cAMP-activated global transcriptional regulator CRP Regulator
  ACKN8U_RS02690 (ACKN8U_02690) - 578494..579285 (-) 792 WP_193282487.1 DUF1338 domain-containing protein -
  ACKN8U_RS02695 (ACKN8U_02695) astD 579528..580985 (-) 1458 WP_005480036.1 succinylglutamate-semialdehyde dehydrogenase -
  ACKN8U_RS02700 (ACKN8U_02700) astA 581014..582033 (-) 1020 WP_005458129.1 arginine N-succinyltransferase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23665.48 Da        Isoelectric Point: 7.8388

>NTDB_id=1079451 ACKN8U_RS02685 WP_005381432.1 577717..578349(+) (crp) [Vibrio parahaemolyticus strain L2181]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEED
QERTAWVRAKSPCEVAEISFKKFRQLIQVNPDILMRLSAQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=1079451 ACKN8U_RS02685 WP_005381432.1 577717..578349(+) (crp) [Vibrio parahaemolyticus strain L2181]
ATGGTTCTAGGTAAACCTCAAACCGACCCAACATTAGAGTGGTTTCTTTCACACTGTCATATTCATAAGTACCCATCAAA
GAGCACGCTAATTCACGCAGGTGAAAAAGCTGAAACGTTGTACTACATCGTTAAAGGCTCTGTTGCGGTTCTTATCAAGG
ACGAAGAAGGTAAGGAAATGATTCTTTCTTACCTAAACCAAGGTGACTTTATTGGTGAACTTGGTCTATTCGAAGAAGAC
CAAGAGCGTACAGCTTGGGTTCGCGCTAAATCTCCTTGTGAAGTTGCTGAAATTTCTTTCAAGAAGTTCCGTCAGCTTAT
CCAAGTAAACCCAGACATCCTAATGCGTCTTTCTGCGCAGATGGCTCGTCGTCTTCAAGTAACTAGCCAAAAAGTGGGTG
ACCTAGCGTTCCTAGACGTAACTGGTCGTATCGCTCAGACGCTTCTGAACCTTGCTAAACAACCAGATGCGATGACTCAC
CCAGACGGCATGCAAATCAAGATCACTCGTCAAGAAATCGGTCAAATCGTTGGCTGTTCTCGTGAGACAGTAGGTCGTAT
CTTGAAGATGCTAGAAGAGCAGAACCTAATCTCTGCGCACGGTAAAACTATCGTTGTTTACGGTACTCGTTAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U2ZZI4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

98.095

100

0.981
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.826

98.571

0.471

Multiple sequence alignment