Detailed information NTG1077350

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACJKIJ_RS24760
• Genome accession: NZ_CP174500
• Coordinates: 5306271..5307608 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain HFL.SG.jS
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5301271..5312608

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJKIJ_RS24735 (ACJKIJ_24735)	pgeF	5301414..5302142 (-)	729	WP_031693031.1	peptidoglycan editing factor PgeF	-
ACJKIJ_RS24740 (ACJKIJ_24740)	rluD	5302139..5303101 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACJKIJ_RS24745 (ACJKIJ_24745)	-	5303247..5304272 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACJKIJ_RS24750 (ACJKIJ_24750)	-	5304429..5304674 (+)	246	WP_009316269.1	PP0621 family protein	-
ACJKIJ_RS24755 (ACJKIJ_24755)	pilS	5304664..5306256 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
ACJKIJ_RS24760 (ACJKIJ_24760)	pilR	5306271..5307608 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACJKIJ_RS24765 (ACJKIJ_24765)	thiO	5307654..5308748 (-)	1095	WP_023084775.1	glycine oxidase ThiO	-
ACJKIJ_RS24770 (ACJKIJ_24770)	-	5308883..5309392 (+)	510	WP_196691309.1	GspH/FimT family pseudopilin	-
ACJKIJ_RS24775 (ACJKIJ_24775)	-	5309498..5310004 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ACJKIJ_RS24780 (ACJKIJ_24780)	pilV	5309995..5310552 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ACJKIJ_RS24785 (ACJKIJ_24785)	pilW	5310549..5311373 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ACJKIJ_RS24790 (ACJKIJ_24790)	pilX	5311370..5311957 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1077350 ACJKIJ_RS24760 WP_003094694.1 5306271..5307608(+) (pilR) [Pseudomonas aeruginosa strain HFL.SG.jS]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1077350 ACJKIJ_RS24760 WP_003094694.1 5306271..5307608(+) (pilR) [Pseudomonas aeruginosa strain HFL.SG.jS]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACTCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384