Detailed information NTG0107565

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EX97_RS09210
• Genome accession: NZ_CP007690
• Coordinates: 1853692..1854681 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain UA-S391_USA300 isolate abscess/wound isolate
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1848692..1859681

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EX97_RS09195 (EX97_08770)	acsA	1849893..1851599 (-)	1707	WP_000862083.1	acetate--CoA ligase	-
EX97_RS09200 (EX97_08775)	-	1851768..1852400 (+)	633	WP_001015996.1	hypothetical protein	-
EX97_RS09205 (EX97_08780)	-	1852425..1853594 (+)	1170	WP_001184005.1	acetoin utilization protein AcuC	-
EX97_RS09210 (EX97_08785)	ccpA	1853692..1854681 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
EX97_RS09215	-	1854754..1854867 (-)	114	WP_001788994.1	hypothetical protein	-
EX97_RS09220 (EX97_08790)	-	1855221..1856312 (-)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
EX97_RS09225	-	1856773..1856877 (-)	105	WP_001791758.1	hypothetical protein	-
EX97_RS09230 (EX97_08795)	-	1857012..1858370 (-)	1359	WP_000193917.1	hypothetical protein	-
EX97_RS09235 (EX97_08800)	-	1858444..1858935 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=107565 EX97_RS09210 WP_000219066.1 1853692..1854681(-) (ccpA) [Staphylococcus aureus strain UA-S391_USA300 isolate abscess/wound isolate]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=107565 EX97_RS09210 WP_000219066.1 1853692..1854681(-) (ccpA) [Staphylococcus aureus strain UA-S391_USA300 isolate abscess/wound isolate]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462