Detailed information NTG1073614

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: ACI5E1_RS08880
• Genome accession: NZ_CP173662
• Coordinates: 1917785..1918441 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain APL2305174E
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1912785..1923441

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACI5E1_RS08860 (ACI5E1_08850)	nanA	1913159..1914037 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
ACI5E1_RS08865 (ACI5E1_08855)	nagB	1914087..1914890 (+)	804	WP_005602606.1	glucosamine-6-phosphate deaminase	-
ACI5E1_RS08870 (ACI5E1_08860)	nagA	1914942..1916087 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
ACI5E1_RS08875 (ACI5E1_08865)	fumC	1916236..1917630 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
ACI5E1_RS08880 (ACI5E1_08870)	sxy/tfoX	1917785..1918441 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
ACI5E1_RS08885 (ACI5E1_08875)	rpsJ	1918849..1919160 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
ACI5E1_RS08890 (ACI5E1_08880)	rplC	1919186..1919812 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
ACI5E1_RS08895 (ACI5E1_08885)	rplD	1919828..1920430 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
ACI5E1_RS08900 (ACI5E1_08890)	rplW	1920427..1920732 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
ACI5E1_RS08905 (ACI5E1_08895)	rplB	1920753..1921574 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
ACI5E1_RS08910 (ACI5E1_08900)	rpsS	1921602..1921877 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
ACI5E1_RS08915 (ACI5E1_08905)	rplV	1921888..1922220 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
ACI5E1_RS08920 (ACI5E1_08910)	rpsC	1922239..1922946 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
ACI5E1_RS08925 (ACI5E1_08915)	rplP	1922960..1923370 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=1073614 ACI5E1_RS08880 WP_005609196.1 1917785..1918441(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain APL2305174E]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=1073614 ACI5E1_RS08880 WP_005609196.1 1917785..1918441(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain APL2305174E]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAATGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376