Detailed information NTG0107353

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACAM22_RS08435
• Genome accession: NZ_AP028929
• Coordinates: 1832840..1833850 (-)
• Length: 336 a.a.
• NCBI ID: WP_001090627.1
• Uniprot ID: I0SX71
• Organism: Streptococcus sp. SN-1
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1827840..1838850

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM22_RS08410 (MASAN616_16350)	-	1827907..1829121 (-)	1215	WP_000666455.1	pyridoxal phosphate-dependent aminotransferase	-
ACAM22_RS08415 (MASAN616_16360)	-	1829278..1829571 (-)	294	WP_369606678.1	hypothetical protein	-
ACAM22_RS08420 (MASAN616_16370)	-	1829733..1830185 (+)	453	WP_000079148.1	universal stress protein	-
ACAM22_RS08425 (MASAN616_16380)	-	1830220..1831608 (-)	1389	WP_369606679.1	Cof-type HAD-IIB family hydrolase	-
ACAM22_RS08430 (MASAN616_16390)	-	1831674..1832636 (+)	963	WP_261066322.1	asparaginase	-
ACAM22_RS08435 (MASAN616_16400)	ccpA	1832840..1833850 (-)	1011	WP_001090627.1	catabolite control protein A	Regulator
ACAM22_RS08440 (MASAN616_16410)	-	1834088..1834405 (+)	318	WP_000886035.1	DUF960 domain-containing protein	-
ACAM22_RS08445 (MASAN616_16420)	folB	1834450..1835262 (-)	813	WP_261052313.1	dihydroneopterin aldolase	-
ACAM22_RS08450 (MASAN616_16430)	folE	1835421..1835975 (-)	555	WP_004247172.1	GTP cyclohydrolase I FolE	-
ACAM22_RS08455 (MASAN616_16440)	-	1835956..1837278 (-)	1323	WP_369606680.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
ACAM22_RS08460 (MASAN616_16450)	folP	1837280..1838254 (-)	975	WP_369606681.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37169.19 Da
• Isoelectric Point: 5.3350

>NTDB_id=107353 ACAM22_RS08435 WP_001090627.1 1832840..1833850(-) (ccpA) [Streptococcus sp. SN-1]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVTYLAKENERIAFVSGPLVDDINGKVRLVGYKEALKKAGISYSEGLVFESKYTYEDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEEFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=107353 ACAM22_RS08435 WP_001090627.1 1832840..1833850(-) (ccpA) [Streptococcus sp. SN-1]
ATGAATACAGACGATACAGTAACGATTTATGATGTCGCCCGTGAAGCAGGAGTTTCAATGGCGACGGTTAGCCGTGTAGT
CAATGGCAATAAGAATGTAAAAGAGAACACCCGTAAAAAAGTGCTTGAGGTGATTGATCGTTTAGATTACCGTCCAAATG
CTGTGGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTGGTGATCCCAAATATTACCAATGGCTATTTCTCA
ACGCTTGCTAAAGGGATTGACGATATCGCTGAAATGTACAAGTATAATATTGTCCTTGCTAATAGTGATGAGGATGATGA
CAAGGAAGTTTCAGTTGTCAATACCCTGTTTTCTAAGCAAGTGGATGGTATCATCTTTATGGGGTACCACTTGACTGAAA
AAATTCGTTCAGAGTTTTCTCGTTCTCGGACACCAGTTGTTCTTGCAGGAACTGTGGATGTAGAACATCAGCTTCCAAGT
GTCAATATTGACTACAAACAAGCAACGATTGATGCAGTAACCTACCTTGCTAAAGAAAATGAGCGCATCGCTTTTGTTAG
CGGTCCACTAGTGGATGACATCAATGGTAAGGTTCGTTTGGTTGGCTACAAGGAAGCCTTGAAAAAAGCAGGTATTTCTT
ATAGCGAAGGATTGGTATTTGAATCTAAGTACACTTATGAAGACGGTTATGCCTTGGCAGAACGCTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTAACAGGTGATGAATTGGCAGCAGGTGTCTTGAACGGCCTTGCTGATAAGGGTGTGTCTGTGCC
AGAAGAGTTTGAAATCATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACTATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTCGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: I0SX71

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	95.536	100	0.955
ccpA	Streptococcus gordonii str. Challis substr. CH1	89.521	99.405	0.89
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	58.006	98.512	0.571