Detailed information NTG0107221

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: AAA995_RS09495
• Genome accession: NZ_AP028877
• Coordinates: 1847376..1848386 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 21P20
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1842376..1853386

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA995_RS09470	-	1843541..1843835 (-)	295	Protein_1853	hypothetical protein	-
AAA995_RS09475 (SP21P20_18670)	-	1843997..1844449 (+)	453	WP_000079148.1	universal stress protein	-
AAA995_RS09480 (SP21P20_18680)	-	1844484..1845872 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
AAA995_RS09485 (SP21P20_18690)	-	1845938..1846900 (+)	963	WP_001124786.1	asparaginase	-
AAA995_RS09490 (SP21P20_18700)	-	1846929..1847312 (-)	384	WP_001092022.1	hypothetical protein	-
AAA995_RS09495 (SP21P20_18710)	ccpA	1847376..1848386 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
AAA995_RS09500 (SP21P20_18720)	-	1848811..1849410 (-)	600	WP_000866703.1	response regulator transcription factor	-
AAA995_RS09505 (SP21P20_18730)	-	1849411..1850508 (-)	1098	WP_000893503.1	sensor histidine kinase	-
AAA995_RS09510 (SP21P20_18740)	-	1850508..1851194 (-)	687	WP_338173871.1	ABC transporter permease	-
AAA995_RS09515 (SP21P20_18750)	-	1851376..1852722 (-)	1347	WP_001808790.1	IS1380-like element ISSpn5 family transposase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=107221 AAA995_RS09495 WP_000990607.1 1847376..1848386(-) (ccpA) [Streptococcus pneumoniae strain 21P20]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=107221 AAA995_RS09495 WP_000990607.1 1847376..1848386(-) (ccpA) [Streptococcus pneumoniae strain 21P20]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568