Detailed information NTG1071635

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACI1PX_RS24045
• Genome accession: NZ_CP173359
• Coordinates: 5147593..5148930 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa isolate CF2843GFP
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5142593..5153930

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACI1PX_RS24020 (ACI1PX_24030)	pgeF	5142736..5143464 (-)	729	WP_014603307.1	peptidoglycan editing factor PgeF	-
ACI1PX_RS24025 (ACI1PX_24035)	rluD	5143461..5144423 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACI1PX_RS24030 (ACI1PX_24040)	-	5144569..5145594 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACI1PX_RS24035 (ACI1PX_24045)	-	5145751..5145996 (+)	246	WP_014603308.1	PP0621 family protein	-
ACI1PX_RS24040 (ACI1PX_24050)	pilS	5145986..5147578 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
ACI1PX_RS24045 (ACI1PX_24055)	pilR	5147593..5148930 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACI1PX_RS24050 (ACI1PX_24060)	thiO	5148976..5150070 (-)	1095	WP_020750388.1	glycine oxidase ThiO	-
ACI1PX_RS24055 (ACI1PX_24065)	-	5150205..5150714 (+)	510	WP_003161431.1	Tfp pilus assembly protein FimT/FimU	-
ACI1PX_RS24060 (ACI1PX_24070)	-	5150820..5151326 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ACI1PX_RS24065 (ACI1PX_24075)	pilV	5151317..5151874 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ACI1PX_RS24070 (ACI1PX_24080)	pilW	5151871..5152695 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ACI1PX_RS24075 (ACI1PX_24085)	pilX	5152692..5153279 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1071635 ACI1PX_RS24045 WP_003094694.1 5147593..5148930(+) (pilR) [Pseudomonas aeruginosa isolate CF2843GFP]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1071635 ACI1PX_RS24045 WP_003094694.1 5147593..5148930(+) (pilR) [Pseudomonas aeruginosa isolate CF2843GFP]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384