Detailed information NTG1071606

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: ACI1GX_RS08900
• Genome accession: NZ_CP173358
• Coordinates: 1919750..1920406 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain APL2305225E
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1914750..1925406

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACI1GX_RS08880 (ACI1GX_08870)	nanA	1915124..1916002 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
ACI1GX_RS08885 (ACI1GX_08875)	nagB	1916052..1916855 (+)	804	WP_005602606.1	glucosamine-6-phosphate deaminase	-
ACI1GX_RS08890 (ACI1GX_08880)	nagA	1916907..1918052 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
ACI1GX_RS08895 (ACI1GX_08885)	fumC	1918201..1919595 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
ACI1GX_RS08900 (ACI1GX_08890)	sxy/tfoX	1919750..1920406 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
ACI1GX_RS08905 (ACI1GX_08895)	rpsJ	1920814..1921125 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
ACI1GX_RS08910 (ACI1GX_08900)	rplC	1921151..1921777 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
ACI1GX_RS08915 (ACI1GX_08905)	rplD	1921793..1922395 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
ACI1GX_RS08920 (ACI1GX_08910)	rplW	1922392..1922697 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
ACI1GX_RS08925 (ACI1GX_08915)	rplB	1922718..1923539 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
ACI1GX_RS08930 (ACI1GX_08920)	rpsS	1923567..1923842 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
ACI1GX_RS08935 (ACI1GX_08925)	rplV	1923853..1924185 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
ACI1GX_RS08940 (ACI1GX_08930)	rpsC	1924204..1924911 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
ACI1GX_RS08945 (ACI1GX_08935)	rplP	1924925..1925335 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=1071606 ACI1GX_RS08900 WP_005609196.1 1919750..1920406(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain APL2305225E]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=1071606 ACI1GX_RS08900 WP_005609196.1 1919750..1920406(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain APL2305225E]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAATGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376